---
abstract: 'Presently, the diagnosis of syphilis is dependent mainly on serological tests. The most widely used screening tests for syphilis are the VDRL and the rapid plasma reagin (RPR) and for confirmation, the fluorescent treponemal antibody (FTA) and the treponema pallidum hemagglutination (TPHA) tests. The four alternative modes for diagnosis of syphilis can be a) VDRL + FTA, b) VDRL + TPHA, c) RPR + FTA and d) RPR + TPHA. Here the author reports an evaluation of cost utility of these tests in medical practice. It is shown that the cost per accurate diagnosis with VDRL + TPH is the least expensive choice. Therefore, this alternative is the best method for serological diagnosis for syphilis, based on medical laboratory economics principles.'
altloc:
  - http://www.ojhas.org/issue25/2008-1-8.htm
chapter: ~
commentary: ~
commref: ~
confdates: ~
conference: ~
confloc: ~
contact_email: ~
creators_id:
  - wviroj@yahoo.com
creators_name:
  - family: Wiwanitkit
    given: Viroj
    honourific: ''
    lineage: ''
date: 2008-04-10
date_type: published
datestamp: 2008-06-02 00:34:22
department: ~
dir: disk0/00/00/60/89
edit_lock_since: ~
edit_lock_until: ~
edit_lock_user: ~
editors_id:
  - Kakkilaya BS
editors_name:
  - family: Kakkilaya
    given: Srinivas
    honourific: Dr.
    lineage: ''
eprint_status: archive
eprintid: 6089
fileinfo: /style/images/fileicons/application_pdf.png;/6089/1/2008%2D1%2D8.pdf
full_text_status: public
importid: ~
institution: ~
isbn: ~
ispublished: pub
issn: ~
item_issues_comment: []
item_issues_count: 0
item_issues_description: []
item_issues_id: []
item_issues_reported_by: []
item_issues_resolved_by: []
item_issues_status: []
item_issues_timestamp: []
item_issues_type: []
keywords: 'Serology, Diagnosis, Syphilis'
lastmod: 2011-03-11 08:57:08
latitude: ~
longitude: ~
metadata_visibility: show
note: ~
number: 1
pagerange: ~
pubdom: TRUE
publication: Online Journal of Health and Allied Sciences
publisher: Dr. B.S. Kakkilaya
refereed: TRUE
referencetext: "1.\tGoh BT. Syphilis in adults. Sex Transm Infect. 2005;81:448-52.\r\n2.\tLowhagen GB. Syphilis: test procedures and therapeutic strategies. Semin Dermatol. 1990;9:152-9.\r\n3.\tWiwanitkit V. Biological false reactive VDRL tests: when to re-test? Southeast Asian J Trop Med Public Health. 2002;33 Suppl 3:131-2. \r\n4.\tZeltser R, Kurban AK. Syphilis. Clin Dermatol. 2004;22:461-8.\r\n5.\tDrusin LM. Syphilis: clinical manifestations, diagnosis, and treatment. Urol Clin North Am. 1984;11:121-30.\r\n6.\tFeder HM Jr, Manthous C. The asymptomatic patient with a positive VDRL test. Am Fam Physician. 1988;37:185-90."
relation_type: []
relation_uri: []
reportno: ~
rev_number: 19
series: ~
source: ~
status_changed: 2008-06-02 00:34:21
subjects:
  - OJHAS
succeeds: ~
suggestions: ~
sword_depositor: ~
sword_slug: ~
thesistype: ~
title: Cost utility analysis of diagnostic method of syphilis
type: journale
userid: 4338
volume: 7
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