creators_name: Kristal, Mark B.
creators_name: Thompson, Alexis C.
creators_name: Heller, Steve B.
creators_name: Komisaruk, Barry R.
creators_id: kristal@buffalo.edu
creators_id: athompso@RIA.Buffalo.EDU
type: journalp
datestamp: 2008-11-02 09:59:45
lastmod: 2011-03-11 08:57:13
metadata_visibility: show
title: Placenta Ingestion Enhances Analgesia
Produced by Vaginal/Cervical
Stimulation in Rats
ispublished: pub
subjects: bio-behav
subjects: psy-bio
subjects: physio-psy
subjects: behav-neuro-sci
full_text_status: public
keywords: Placenta, Pain, Opiates, Vaginal stimulation-produced analgesia, Tail-flick test, Afterbirth,
Analgesia, Parturition, Placentophagia, VSPA, Vaginal/cervical stimulation, POEF
abstract: Ingestion of placenta has previously been shown to enhance opiate-mediated analgesia (measured as tail-flick latency) induced either by morphine injection or by footshock. The present study was designed to test whether placenta ingestion would enhance the partly opiate-mediated analgesia produced by vaginal/cervical stimulation. Nulliparous Sprague-Dawley rats were tested for analgesia, using tail-flick latency, during and after vaginal/cervical stimulation; the tests for vaginal/cervical stimulation-induced analgesia were administered both before and after the rats ate placenta or ground beef. Placenta ingestion, but not beef ingestion. significantly heightened vaginal/cervical stimulation-induced analgesia. A subsequent morphine injection provided evidence that, as in a previous report, placenta ingestion, but not beef ingestion, enhanced morphine-induced analgesia.
date: 1986
date_type: published
publication: Physiology & Behavior
volume: 36
number: 6
publisher: Pergamon Press
pagerange: 1017-1020
refereed: TRUE
citation:   Kristal, Dr. Mark B. and Thompson, Alexis C. and Heller, Steve B. and Komisaruk, Dr. Barry R.  (1986) Placenta Ingestion Enhances Analgesia Produced by Vaginal/Cervical Stimulation in Rats.  [Journal (Paginated)]     
document_url: http://cogprints.org/6254/1/VSIA.pdf