?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Effect+of+fish+oil+on+lipopolysaccharide-induced+hydroxyapatite+loss+in+rat+alveolar+bone%3A+A+Preliminary+Study&rft.creator=Indahyani%2C+Didin+E&rft.creator=Santoso%2C+AL+Supartinah&rft.creator=Utoro%2C+Totok&rft.creator=Soesatyo%2C+Marsetyawan+HNE&rft.creator=Sosroseno%2C+Wihaskoro&rft.subject=Online+Journal+of+Health+and+Allied+Sciences&rft.description=Dietary+fish+oil+has+been+shown+to+inhibit+bone+resorption+and%2C+therefore%2C+the+aim+of+the+present+study+was+to+test+the+hypothesis+that+fish+oil+alters+lipopolysaccharide+(LPS)-induced+hydroxyapatite+loss+in+rat+alveolar+bone.+Rats+were+divided+into+four+groups.+The+animals+injected+with+saline+or+Escherichia+coli-derived+LPS+into+the+maxillary+alveolar+mucosa+on+the+buccoapical+site+of+the+molar+region+daily+for+8+days+were+served+as+a+negative+or+positive+control%2C+respectively.+Other+groups+of+animals+were+injected+with+LPS+and+orally+treated+with+fish+oil+at+the+same+day+with+or+after+LPS+injection.+The+results+of+the+present+study+showed+that+the+hydroxyapatite+contents+of+alveolar+bone+in+rats+treated+with+fish+oil+at+the+same+day+with+or+before+LPS+injection+were+significantly+higher+than+those+in+rats+injected+with+LPS+alone%2C+but+still+lower+than+those+in+untreated+animals.+Therefore%2C+the+present+study+suggests+that+oral+treatment+with+fish+oil+may+reduce+LPS-induced+hydroxyapatite+loss+in+rat+alveolar+bone&rft.publisher=Dr.+B.S.+Kakkilaya&rft.contributor=Kakkilaya%2C+Dr.+Srinivas&rft.date=2009-02-25&rft.type=Journal+(On-line%2FUnpaginated)&rft.type=PeerReviewed&rft.format=application%2Fpdf&rft.identifier=http%3A%2F%2Fcogprints.org%2F6394%2F1%2F2008-4-7.pdf&rft.identifier=++Indahyani%2C+Didin+E+and+Santoso%2C+AL+Supartinah+and+Utoro%2C+Totok+and+Soesatyo%2C+Marsetyawan+HNE+and+Sosroseno%2C+Wihaskoro++(2009)+Effect+of+fish+oil+on+lipopolysaccharide-induced+hydroxyapatite+loss+in+rat+alveolar+bone%3A+A+Preliminary+Study.++%5BJournal+(On-line%2FUnpaginated)%5D+++++&rft.relation=http%3A%2F%2Fcogprints.org%2F6394%2F