?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Study+of+Early+Predictors+of+Fatality+in+Mechanically+Ventilated+Neonates+in+NICU&rft.creator=Trivedi%2C+SS&rft.creator=Chudasama%2C+RK&rft.creator=Srivastava%2C+A&rft.subject=Online+Journal+of+Health+and+Allied+Sciences&rft.description=Objective%3A+To+evaluate+the+risk+factors+associated+with+fatality+in+mechanically+ventilated+neonates+using+multiple+regression+analysis.+Design+%26+settings%3A+Prospective+study+conducted+at+Neonatal+ICU+at+New+Civil+Hospital%2C+Surat+%E2%80%93+a+tertiary+care+centre%2C+from+December%2C+2007+to+May%2C+2008+for+6+months.+Methods%3A+Fifty+neonates+in+NICU+consecutively+put+on+mechanical+ventilator+during+study+period+were+enrolled+in+the+study.+The+pressure+limited+time+cycled+ventilator+was+used.+All+admitted+neonates+were+subjected+to+an+arterial+blood+gas+analysis+along+with+a+set+of+investigations+to+look+for+pulmonary+maturity%2C+infections%2C+renal+function%2C+hyperbilirubinemia%2C+intraventricular+hemorrhage+and+congenital+anomalies.+Different+investigation+facilities+were+used+as+and+when+required+during+ventilation+of+neonates.+Multiple+logistic+regression+analysis+was+done+to+find+out+the+predictors+of+fatality+among+these+neonates.+Results%3A+Various+factors+suspected+as+predictors+of+fatality+of+mechanically+ventilated+neonates+were+assessed.+Hypothermia%2C+prolonged+capillary+refill+time+(CRT)%2C+initial+requirement+of+oxygen+fraction+(FiO2)+%3E0.6%2C+alveolar+to+arterial+PO2+difference+(AaDO2)+%3E250%2C+alveolar+to+arterial+PO2+ratio+(a%2FA)+%3C0.25%2C+%26+oxygenation+index+(OI)+%3E10+were+found+statistically+highly+significant+predictors+of+mortality+among+mechanically+ventilated+neonates.+Conclusion%3A+Hypothermia+and+prolonged+capillary+refill+time+were+independent+predictors+of+fatality+in+neonatal+mechanical+ventilation.+Risk+of+fatality+can+be+identified+in+mechanically+ventilated+neonates.&rft.publisher=Dr.+BS+Kakkilaya&rft.contributor=Kakkilaya%2C+Dr+Srinivas&rft.date=2009-11-15&rft.type=Journal+(On-line%2FUnpaginated)&rft.type=PeerReviewed&rft.format=application%2Fpdf&rft.identifier=http%3A%2F%2Fcogprints.org%2F6956%2F1%2F2009-3-9.pdf&rft.identifier=++Trivedi%2C+SS+and+Chudasama%2C+RK+and+Srivastava%2C+A++(2009)+Study+of+Early+Predictors+of+Fatality+in+Mechanically+Ventilated+Neonates+in+NICU.++%5BJournal+(On-line%2FUnpaginated)%5D+++++&rft.relation=http%3A%2F%2Fcogprints.org%2F6956%2F