?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Inherited+hemolytic+disorders+with+high+occurrence+of+b-thalassemia+in+Sindhi+community+of+Jabalpur+town+in+Madhya+Pradesh%2C+India&rft.creator=Balgir%2C+RS&rft.subject=Online+Journal+of+Health+and+Allied+Sciences&rft.description=Hereditary+hemolytic+disorders+such+as+hemoglobin+disorders%2C+%CE%B2-thalassemia+syndrome%2C+G6PD+deficiency%2C+and+ABO+and+Rhesus+blood+groups+are+the+most+common+public+health+problems+in+India.+Community+genetic+screening+provides+multifaceted+information+for+finding+prevalence%2C+level+of+health+education%2C+preventive+strategies+such+as+genetic%2Fmarriage+counseling+to+relieve+the+burden+of+vulnerable+communities.+However%2C+such+genetic+screening+studies+are+scanty+in+India.+This+study+aims+to+find+the+prevalence+of+inherited+hemolytic+disorders+in+Sindhi+community%2C+identify+the+persons+for+genetic%2Fmarriage+counseling+and+to+suggest+the+relevant+strategies+for+prevention+and+control+to+the+affected+families.+A+cross-sectional+random+study+of+508+persons+of+Sindhi+community+belonging+to+all+ages+and+both+sexes+was+conducted+for+screening+of+hemoglobin+disorders%2C+G6PD+deficiency+and+ABO+and+Rhesus+(D)+blood+groups+following+the+standard+procedures+and+techniques+from+Jabalpur+town+in+Central+India.+High+frequency+of+%CE%B2-thalassemia+trait+(20.5%25)%2C+Hb+D+trait+(2.2%25)+and+hemoglobin+D%2F%CE%B2-thalassemia+(0.2%25)%2C+G6PD+deficiency+(0.8%25)%2C+and+a+low+prevalence+of+Rhesus+negative+(3.0%25)+blood+group+was+observed+in+Sindhi+community+of+Jabalpur+town+in+Madhya+Pradesh.+A+case+of+%CE%B2-thalassemia+major+and+Hb+D-thalassemia+were+also+encountered.+Double+heterozygosity+of+Hb+D%2F%CE%B2-thalassemia+showed+hypochromic+and+microcytic+red+cell+morphology+with+mild+anemia.+Inherited+hemolytic+disorders+are+an+important+public+health+challenge+in+Sindhi+community.+Preventive+genetics+program+needs+to+be+vigorously+taken+up+to+ameliorate+the+sufferings+of+at+risk+communities+in+India.&rft.publisher=Dr.+BS+Kakkilaya&rft.contributor=Kakkilaya%2C+Dr+Srinivas&rft.date=2010-04-30&rft.type=Journal+(On-line%2FUnpaginated)&rft.type=PeerReviewed&rft.format=application%2Fpdf&rft.identifier=http%3A%2F%2Fcogprints.org%2F6973%2F1%2F2009-4-5.pdf&rft.identifier=++Balgir%2C+RS++(2010)+Inherited+hemolytic+disorders+with+high+occurrence+of+b-thalassemia+in+Sindhi+community+of+Jabalpur+town+in+Madhya+Pradesh%2C+India.++%5BJournal+(On-line%2FUnpaginated)%5D+++++&rft.relation=http%3A%2F%2Fcogprints.org%2F6973%2F