<> "The repository administrator has not yet configured an RDF license."^^ . <> . . "Total Thiols and MDA Levels in Patients with Acute Myocardial Infarction Before and After Reperfusion Therapy"^^ . "Background: Reactive oxygen species have been implicated in the pathogenesis of ischemic and reperfusion injury. In the current work we have measured malondialdehyde (MDA), total thiols, total CK, CK-MB and AST in ECG proven acute myocardial infarction (AMI) patients immediately after admission and 24 hours after administration of thrombolytic agent streptokinase, and in healthy controls. Methods: Blood samples from 44 AMI patients and 25 age and sex matched healthy controls were obtained and analyzed for MDA, total thiols using spectrophotometric methods and cardiac enzymes CK, CK-MB and AST using automated analyzer. Results: We have found significant increase in MDA, CPK, CK-MB, AST (p< 0.001) and significant decrease in total thiols (p<0.001) in AMI patients after thrombolytic therapy compared to values at admission, and healthy controls. MDA correlated negatively with total thiols (r = - 0.333, p<0.05) and positively with CK-MB (r = 0.491, p<0.01) in AMI patients after thrombolytic therapy. Conclusions: Reperfusion following thrombolytic therapy increases reactive oxygen species with concomitant decrease in antioxidant total thiols."^^ . "2010-10-15" . . "9" . "3" . . "Dr. B.S. Kakkilaya"^^ . . . "Online Journal of Health and Allied Sciences"^^ . . . . . . . . . . . . . . . . . "Jeevan K"^^ . "Shetty"^^ . "Jeevan K Shetty"^^ . . "Srinivas"^^ . "Kakkilaya"^^ . "Srinivas Kakkilaya"^^ . . "Suresh"^^ . "Babu"^^ . "Suresh Babu"^^ . . "Prakash"^^ . "Mungli"^^ . "Prakash Mungli"^^ . . . . . . "Total Thiols and MDA Levels in Patients with Acute Myocardial Infarction Before and After Reperfusion Therapy (PDF)"^^ . . . . . . . . . . . . "2010-3-6.pdf"^^ . . . "Total Thiols and MDA Levels in Patients with Acute Myocardial Infarction Before and After Reperfusion Therapy (Image (JPEG))"^^ . . . . . . "preview.jpg"^^ . . . "Total Thiols and MDA Levels in Patients with Acute Myocardial Infarction Before and After Reperfusion Therapy (Indexer Terms)"^^ . . . . . . "indexcodes.txt"^^ . . "HTML Summary of #6978 \n\nTotal Thiols and MDA Levels in Patients with Acute Myocardial Infarction Before and After Reperfusion Therapy\n\n" . "text/html" . . . "Online Journal of Health and Allied Sciences" . .