?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Physiological+antioxidant+system+and+oxidative+stress+in+stomach+cancer+patients+with+normal+renal+and+hepatic+function&rft.creator=Reddy%2C+EP&rft.creator=Reddy%2C+VS&rft.creator=Chandra+Mouli%2C+K&rft.creator=Rao%2C+PVLNS&rft.subject=Online+Journal+of+Health+and+Allied+Sciences&rft.description=Role+of+free+radicals+has+been+proposed+in+the+pathogenesis+of+many+diseases.+Gastric+cancer+is+a+common+disease+worldwide%2C+and+leading+cause+of+cancer+death+in+India.+Severe+oxidative+stress+produces+reactive+oxygen+species+(ROS)+and+induces+uncontrolled+lipid+peroxidation.+Albumin%2C+uric+acid+(UA)+and+Bilirubin+are+important+physiological+antioxidants.+We+aimed+to+evaluate+and+assess+the+role+of+oxidative+stress+(OS)+and+physiological+antioxidant+system+in+stomach+cancer+patients.+Lipid+peroxidation+measured+as+plasma+Thio+Barbituric+Acid+Reactive+substances+(TBARS)%2C+was+found+to+be+elevated+significantly+(p%3D0.001)+in+stomach+cancer+compared+to+controls+along+with+a+decrease+in+plasma+physiological+antioxidant+system.+The+documented+results+were+due+to+increased+lipid+peroxidation+and+involvement+of+physiological+antioxidants+in+scavenging+free+radicals+but+not+because+of+impaired+hepatic+and+renal+functions.&rft.publisher=Dr.+BS+Kakkilaya&rft.contributor=Kakkilaya%2C+Dr+Srinivas&rft.date=2010-04-30&rft.type=Journal+(On-line%2FUnpaginated)&rft.type=PeerReviewed&rft.format=application%2Fpdf&rft.identifier=http%3A%2F%2Fcogprints.org%2F6979%2F1%2F2009-4-9.pdf&rft.identifier=++Reddy%2C+EP+and+Reddy%2C+VS+and+Chandra+Mouli%2C+K+and+Rao%2C+PVLNS++(2010)+Physiological+antioxidant+system+and+oxidative+stress+in+stomach+cancer+patients+with+normal+renal+and+hepatic+function.++%5BJournal+(On-line%2FUnpaginated)%5D+++++&rft.relation=http%3A%2F%2Fcogprints.org%2F6979%2F