---
abstract: 'Malignant peripheral nerve sheath tumors (MPNST’S) of the head and neck comprise 2% to 6% of head and neck sarcomas. These tumors may arise as sporadic variants or in patients with neurofibromatosis (NF). Development of these MPNST’s is one of the serious complications of neurofibromatosis type 1(NF1). To our knowledge there are only two reported cases of MPNST’s arising in the cervical vagal nerve, occurring in NF1 patients. We present here an NF1 patient who developed an MPNST of the cervical vagus nerve and presented only with a cervical swelling and hoarseness.'
altloc:
  - http://www.ojhas.org/issue33/2010-1-10.htm
chapter: ~
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contact_email: ~
creators_id:
  - ~
  - drsandeepb@rediffmail.com
  - ~
  - ~
creators_name:
  - family: Gupta
    given: A
    honourific: ''
    lineage: ''
  - family: Bansal
    given: S
    honourific: ''
    lineage: ''
  - family: Bhagat
    given: S
    honourific: ''
    lineage: ''
  - family: Bahl
    given: A
    honourific: ''
    lineage: ''
date: 2010-07-30
date_type: published
datestamp: 2010-09-13 03:52:50
department: ~
dir: disk0/00/00/69/96
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editors_id:
  - Kakkilaya BS
editors_name:
  - family: Kakkilaya
    given: Srinivas
    honourific: Dr
    lineage: ''
eprint_status: archive
eprintid: 6996
fileinfo: /style/images/fileicons/application_pdf.png;/6996/1/2010%2D1%2D10.pdf
full_text_status: public
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ispublished: pub
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item_issues_comment: []
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keywords: 'Peripheral nerve sheath tumor, malignant, neurofibromatosis, vagus nerve '
lastmod: 2011-03-11 08:57:43
latitude: ~
longitude: ~
metadata_visibility: show
note: ~
number: 1
pagerange: ~
pubdom: TRUE
publication: Online Journal of Health and Allied Sciences
publisher: Dr. B.S. Kakkilaya
refereed: TRUE
referencetext: "1.\tMolina A.R, Brasch H, et al. Malignant peripheral nerve sheath tumor of the cervical vagus nerve in a neurofibromatosis type 1 patient. Journal of Plastic, Reconstructive & Aesthetic Surgery 2000;59:1458-1462. \r\n2.\tKuzu Y, Beppu T,Sibanai K, et al. A malignant peripheral nerve sheath tumor originating from the cervical vagus nerve. No Shinkei Geka May 2002;30(5):523-6 [in Japanese]. \r\n3.\tRamanathan RC, Thomas JM .Malignant peripheral nerve sheath tumours associated with von Recklinghausen’s neurofibromatosis. Eur J Surg Oncol Apr 1999;25(2):190-3.\r\n4.\tKing AA, Debaun MR, Riccardi VM, et al. Malignant peripheral nerve sheath tumours in neurofibromatosis 1. Am J Med Genet 2000;93(5):388-92.\r\n5.\tGlimer-Hill HS, Kline DG. Neurogenic tumours of the cervical vagus nerve; report of four cases and review of literature. Neurosurgery Jun 2000;46(6):1498-503.\r\n6.\tDucatman BS, Scheithauer BW, Piepgras DG, et al. Malignant peripheral nerve sheath tumours. A clinicopathological study of 120 cases. Cancer May 15, 1986;57(10):2006-21. \r\n7.\tLoree TR, North Jr Jh, Werness BA, et al. Malignant peripheral nerve sheath tumors of the head and neck: analysis of prognostic factors. Otolaryngol Head Neck Surg 2000 May;122 (5);667-72.\r\n8.\tMark RJ, Bailet JW,Poen J, et al. Postirradiation sarcoma of head and neck. Cancer 1993;72:887-93.\r\n9.\tFerner RE, Gutmann DH. International consensus statement on malignant peripheral nerve sheath tumors in neurofibromatosis1. Cancer Res Mar 2002;62:1573-7.\r\n10.\tGreager JA, Reichard KW, Campana JP, et al. Malignant schwannoma of head and neck. Am J Surg 1992;163:440-2.\r\n11.Hoffmann DF, Everts EC, Smith JD, et al. Malignant sheath tumours of the head and neck. Otolaryngol Head Neck Surg 1988;99:309-14"
relation_type: []
relation_uri: []
reportno: ~
rev_number: 20
series: ~
source: ~
status_changed: 2010-09-13 03:52:50
subjects:
  - OJHAS
succeeds: ~
suggestions: ~
sword_depositor: ~
sword_slug: ~
thesistype: ~
title: 'Malignant peripheral nerve sheath tumor of the cervical vagus nerve in a neurofibromatosis type 1 patient - An unusual presentation'
type: journale
userid: 4338
volume: 9
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