?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Butorphanol+for+Post-Operative+Analgesia+-+A+Comparative+Clinical+Study+with+Ketorolac&rft.creator=Tantry%2C+Thrivikrama+Padur&rft.creator=Vastrad%2C+Nandish+S&rft.creator=Koteshwar%2C+Reshma&rft.creator=Mohan%2C+Prashanth&rft.creator=Kadri%2C+Rajani&rft.creator=Kadam%2C+Dinesh&rft.creator=Adappa%2C+Karunakara&rft.creator=Shenoy%2C+Sunil+P&rft.subject=Online+Journal+of+Health+and+Allied+Sciences&rft.description=Introduction%3A+Butorphanol%2C+an+opioid+derivative+has+been+shown+to+have%2C+in+addition+to+its+analgesic+properties%2C+several+other+advantageous+effects+like+antistressor%2C+sedative+and+anti-shivering+action.+The+efficacy+and+safety+profile+of+ketorolac%2C+yet+another+widely+used+post-operative+analgesic+is+well+documented.+This+study+aims+to+compare+the+two+analgesics.+Aims+and+objectives%3A+This+study+was+conducted+to+compare+the+analgesic+efficacy+and+other+effects+of+butorphanol+and+ketorolac%2C+administered+intramuscularly%2C+in+post-operative+patients+who+have+undergone+lower+abdominal+and+pelvic+surgeries.+Materials+and+methods%3A+50+patients+undergoing+lower+abdominal+and+pelvic+surgeries+under+general+or+spinal+anaesthesia+were+randomly+divided+into+two+Groups+(25+each).+At+a+particular+level+of+post-operative+pain%2C+the+patients+Groups+I+and+II+were+administered+intramuscular+ketorolac+30mg+and+butorphanol+2mg+respectively.+The+analgesic+effect+was+studied+using+Visual+Analogue+Scale+(VAS)+and+the+verbal+category+scale.+Patients+were+monitored+for+the+sedative+action%2C+respiratory+status+and+other+vital+parameters+for+300+minutes+and+for+other+adverse+reactions+over+the+next+twelve+hours.+Observations%3A+Butorphanol+provided+better+analgesia+within+the+first+two+hours+of+administration%2C+while+ketorolac+was+more+effective+at+4-5+hours.+Better+sedative+action+without+any+significant+respiratory+depressant+effect+was+demonstrated+with+butorphanol.+There+were+no+clinically+significant+hemodynamic+fluctuations+or+adverse+reactions+with+butorphanol+or+ketorolac.+Conclusions%3A+Butorphanol+provides+better+early+analgesia+as+compared+to+ketorolac+with+a+desirable+and+safe+sedative+effect+in+post-operative+patients+who+have+undergone+lower+abdominal+and+pelvic+surgeries.&rft.publisher=Dr.+B.S.+Kakkilaya&rft.contributor=Kakkilaya%2C+Dr.+Srinivas&rft.date=2010-10-15&rft.type=Journal+(On-line%2FUnpaginated)&rft.type=PeerReviewed&rft.format=application%2Fpdf&rft.identifier=http%3A%2F%2Fcogprints.org%2F7113%2F1%2F2010-3-9.pdf&rft.identifier=++Tantry%2C+Thrivikrama+Padur+and+Vastrad%2C+Nandish+S+and+Koteshwar%2C+Reshma+and+Mohan%2C+Prashanth+and+Kadri%2C+Rajani+and+Kadam%2C+Dinesh+and+Adappa%2C+Karunakara+and+Shenoy%2C+Sunil+P++(2010)+Butorphanol+for+Post-Operative+Analgesia+-+A+Comparative+Clinical+Study+with+Ketorolac.++%5BJournal+(On-line%2FUnpaginated)%5D+++++&rft.relation=http%3A%2F%2Fcogprints.org%2F7113%2F