---
abstract: 'Gastrointestinal stromal tumors (GIST) are relatively rare tumors of gastrointestinal (GI) tract, most commonly arise from the stomach followed by small intestine and colon, clinically GIST present with occult GI bleeding, abdominal pain and intestinal obstruction. We present a case of a jejunal GIST, which presented as an obscure GI haemorrhage. This case highlights how oesophagogastrodudenectomy and colonoscopy proved inconclusive in determining source of bleeding and the importance of RBC labeled 99m-Tc scan in detecting the source of  GI bleeding and also emphasizes on histopathology and immunohistochemistry in diagnosis of GIST'
altloc:
  - http://www.ojhas.org/issue35/2010-3-21.htm
chapter: ~
commentary: ~
commref: ~
confdates: ~
conference: ~
confloc: ~
contact_email: ~
creators_id:
  - dr.pkshetty@gmail.com
  - ~
  - ~
  - ~
creators_name:
  - family: Shetty
    given: Prasad K
    honourific: ''
    lineage: ''
  - family: Baliga
    given: Sameer V
    honourific: ''
    lineage: ''
  - family: K
    given: Balaiah
    honourific: ''
    lineage: ''
  - family: S
    given: Gnana Prakash
    honourific: ''
    lineage: ''
date: 2010-10-15
date_type: published
datestamp: 2010-11-22 14:19:00
department: ~
dir: disk0/00/00/71/22
edit_lock_since: ~
edit_lock_until: 0
edit_lock_user: ~
editors_id:
  - Kakkilaya BS
editors_name:
  - family: Kakkilaya
    given: Srinivas
    honourific: Dr.
    lineage: ''
eprint_status: archive
eprintid: 7122
fileinfo: /style/images/fileicons/application_pdf.png;/7122/1/2010%2D3%2D21.pdf
full_text_status: public
importid: ~
institution: ~
isbn: ~
ispublished: pub
issn: ~
item_issues_comment: []
item_issues_count: 0
item_issues_description: []
item_issues_id: []
item_issues_reported_by: []
item_issues_resolved_by: []
item_issues_status: []
item_issues_timestamp: []
item_issues_type: []
keywords: Gastrointestinal stromal tumor; RBC labeled 99m-Tc scan; Immunohistochemistry
lastmod: 2011-03-11 08:57:48
latitude: ~
longitude: ~
metadata_visibility: show
note: ~
number: 3
pagerange: ~
pubdom: TRUE
publication: Online Journal of Health and Allied Sciences
publisher: Dr. B.S. Kakkilaya
refereed: TRUE
referencetext: "1.\tMiettinen M, Lasota J. Gastrointestinal stromal tumours-definition, clinical, histological, immunohistochemical, and molecular genetic features and differential diagnosis. Virchows Arch 2001 Jan;438(1):1-12.   \r\n2.\tSpiller RC, Parkins RA. Recurrent gastrointestinal bleeding of obscure origin: report of 17 cases and a guide to logical management. Br J Surg 1983 Aug;70(8):489-493.   \r\n3.\tFox VL. Gastrointestinal bleeding in infancy and childhood. Gastroenterol Clin North Am 2000;29:37–66.\r\n4.\tSuster S. Gastrointestinal stromal tumors: Radiologic Features with Pathologic Correlation. Semin Diagn Pathol 1996;13:297-313.\r\n5.\tMucciarini C, Rossi G, Bertolini F, Valli R, Cirilli C, Rashid I et al. Incidence and clinicopathologic features of gastrointestinal stromal tumours. A population-based study. BMC Cancer 2007;7:230.\r\n6.\tHadithi M, Heine GD, Jacobs MA, Van Bodegraven AA, Mulder CJ. A prospective study comparing video capsule endoscopy with double balloon enteroscopy in patients with obscure gastrointestinal bleeding. Am J Gatroenterol 2006;101:52–57.\r\n7.\tConnolly EM, Gaffney E, Reynolds JV. Gastrointestinal stromal tumors. Br. J Surg 2003;90:1178- 1186. \r\n8.\tGraadt van Roggen JF, van Velthuysen MLF Hogendoorn PC. The histopathological differential diagnosis of gastrointestinal stromal tumors. J Clin Pathol 2001;54:96- 102.\r\n9.\tSircar K, Hewlett BR, Huizinga JD, Chorneyko K, Berezin I, Riddel RH. Interstitial cells of Cajal as precursors of gastrointestinal stromal tumors. AM J Surg Pathol 1999;23:377- 389.\r\n10.\tAmin MB, Ma CK, Linden MD, Kubus JJ, Zarbo RJ. Prognostic value of proliferating cell nuclear antigen index in gastric stromal tumors. Correlation with mitotic count and clinical outcome. Am J Clin Pathol 1993;100:428-32.\r\n11.\tSuster S, Sorace D, Moran CA. Gastrointestinal stromal tumors with prominent myxoid matrix. Clinicopathologic, immunohistochemical, and ultrastructural study of nine cases of a distinctive morphologic variant of myogenic stromal tumor. Am J Surg Pathol 1995;19:59-70.\r\n12.\tSaul SH, Rast ML, Brooks JJ. The immunohistochemistry of gastrointestinal stromal tumors. Evidence supporting an origin from smooth muscle. Am J Surg Pathol 1987;11:464-473."
relation_type: []
relation_uri: []
reportno: ~
rev_number: 35
series: ~
source: ~
status_changed: 2010-11-22 14:19:00
subjects:
  - OJHAS
succeeds: ~
suggestions: ~
sword_depositor: ~
sword_slug: ~
thesistype: ~
title: 'Role of RBC labeled 99m-Tc scan, Histopathology and Immunohistochemistry in Diagnosis of Jejunal Gastrointestinal Stromal Tumor presenting as obscure gastrointestinal haemorrhage'
type: journale
userid: 4338
volume: 9
<script src='https://archive-bar.soton.ac.uk/archive-bar.js'></script>
<script src='https://archive-bar.soton.ac.uk/google-analytics.js'></script>