?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Study+of+Plasma+Ascorbic+Acid+Levels+in+Wheezing+Children&rft.creator=Nagdeote%2C+AN&rft.creator=Paunipagar%2C+PV&rft.creator=Muddeshwar%2C+MG&rft.creator=Suryawanshi%2C+NP&rft.subject=Online+Journal+of+Health+and+Allied+Sciences&rft.description=Background%3A+Reactive+Oxygen+species+induced+bronchial+abnormalities+may+have+important+consequences+in+asthma%2C+the+main+symptom+being+wheezing+specially+in+children.+Vitamin+C+is+an+important+antioxidant+known+to+quench+the+reactive+oxygen+species.+A+beneficial+effect+of+fresh+fruit+consumption+on+lung+function+has+been+observed+in+several+studies.+Plasma+levels+Vitamin+C+was+determined+in+relation+to+wheezing+symptoms+in+cross+sectional+study.+Methods%3A+In+a+cross+sectional+blood+samples+of+50++patients+attending+pediatrics+OPD%2C+having+wheezing+and+shortness+of+breath+were+analyzed+for+plasma+Ascorbic+acid+level+and+compared++with+healthy+controls+of+same+age+and+sex.+Results%3A+The+total+number+of+50+wheezing+children+were+in+the+age+group+of+2+to+12+years+with+similar+age+matched+controls.+It+was+observed+that+the+plasma+ascorbic+acid+concentration+in+the+wheezing+children+(0.43+%E2%80%93+0.12+mg%2Fdl)+was+significantly+decreased+as+compared+to+the+normal+controls+(+0.75+%E2%80%93+0.18+mg%2Fdl+)+P%3C+0.001.+The+highly+significant+low+levels+of+plasma+ascorbic+acid+level+in+wheezing+children+was+irrespective+of+sex+and+severity+of+symptoms.+However+the+ascorbic+acid+levels+were+at+the+lower+side+in+female+and+with+severe+symptoms.+Conclusions%3A+Plasma+Ascorbic+acid+levels+were+significantly%2C+decreased+in+the+process+of+scavenging+the+reactive+oxygen+species.+Ascorbic+acid+directly+neutralizes+free+radical+and+protects+the+bronchial+tissue+from+oxidative+injury%2C+so+it+can+be+concluded+that+the+consumption+of+fruit+rich+in+vitamin+C+may+reduce+wheezing+symptoms+in+children.&rft.publisher=BS+Kakkilaya&rft.contributor=Kakkilaya%2C+Dr+Srinivas&rft.date=2011-01-20&rft.type=Journal+(On-line%2FUnpaginated)&rft.type=PeerReviewed&rft.format=application%2Fpdf&rft.identifier=http%3A%2F%2Fcogprints.org%2F7253%2F1%2F2010-4-10.pdf&rft.identifier=++Nagdeote%2C+AN+and+Paunipagar%2C+PV+and+Muddeshwar%2C+MG+and+Suryawanshi%2C+NP++(2011)+Study+of+Plasma+Ascorbic+Acid+Levels+in+Wheezing+Children.++%5BJournal+(On-line%2FUnpaginated)%5D+++++&rft.relation=http%3A%2F%2Fcogprints.org%2F7253%2F