@misc{cogprints7254, volume = {9}, number = {4}, month = {January}, author = {Deepa S and Amruta Kumari B and Venkatesha D}, editor = {Dr Srinivas Kakkilaya}, title = {Increasing Trends of Methicillin Resistant Coagulase Negative Staphylococcus in Neonatal Septicaemia - A Study in a Tertiary Care Hospital, Mysore, South India}, publisher = {BS Kakkilaya}, year = {2011}, journal = {Online Journal of Health and Allied Sciences}, keywords = {Neonatal septicaemia; Coagulase Negative Staphylococcus; Methicillin resistance}, url = {http://cogprints.org/7254/}, abstract = {Introduction: Neonatal septicaemia is one among the leading causes of neonatal mortality in India. For the last 20 years CoNS has been identified as a major cause of neonatal septicaemia in NICU. Different studies show 70-75\% of CoNS as resistant to methicillin. Material and methods: Blood samples from neonatal septicaemia cases during Dec 2007 to Dec 2010 were processed \& isolates were identified. CoNS were biotyped \& methicillin resistance was detected using cefoxitin 30 ?g disk. Results: Of 2256 blood samples from neonatal septicaemia cases, 587(36.98\%) were CoNS. Staphylococcus epidermidis 234(39.86\%) was the commonest isolate. Methicillin resistance was noted in 286 (48.72\%). MRCoNS prevalence during 2008, 2009 \& 2010 were 41.57\%, 47\% and 57.36\% respectively. Conclusion: Our study showed increased trends of MR-CoNS in neonatal septicaemia leading to increased usage of vancomycin \& other glycopeptides, resulting in emergence of multidrug resistant strains, thus narrowing the treatment options in neonates.} }