"7254","Increasing Trends of Methicillin Resistant Coagulase Negative Staphylococcus in Neonatal Septicaemia - A Study in a Tertiary Care Hospital, Mysore, South India","Introduction: Neonatal septicaemia is one among the leading causes of neonatal mortality in India. For the last 20 years CoNS has been identified as a major cause of neonatal septicaemia in NICU. Different studies show 70-75% of CoNS as resistant to methicillin. Material and methods: Blood samples from neonatal septicaemia cases during Dec 2007 to Dec 2010 were processed & isolates were identified. CoNS were biotyped & methicillin resistance was detected using cefoxitin 30 µg disk. Results: Of 2256 blood samples from neonatal septicaemia cases, 587(36.98%) were CoNS. Staphylococcus epidermidis 234(39.86%) was the commonest isolate. Methicillin resistance was noted in 286 (48.72%). MRCoNS prevalence during 2008, 2009 & 2010 were 41.57%, 47% and 57.36% respectively. Conclusion: Our study showed increased trends of MR-CoNS in neonatal septicaemia leading to increased usage of vancomycin & other glycopeptides, resulting in emergence of multidrug resistant strains, thus narrowing the treatment options in neonates.","http://cogprints.org/7254/","S, Deepa and B, Amruta Kumari and D, Venkatesha","Kakkilaya, Dr Srinivas"," S, Deepa and B, Amruta Kumari and D, Venkatesha (2011) Increasing Trends of Methicillin Resistant Coagulase Negative Staphylococcus in Neonatal Septicaemia - A Study in a Tertiary Care Hospital, Mysore, South India. [Journal (On-line/Unpaginated)] ","drdeepa_intel@yahoo.co.in,,","2011-01-20"