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abstract: Congenital Insensitivity to Pain belongs to the family of Hereditary Sensory and Autonomic Neuropathies (HSAN). It is a rare disorder of unknown etiology associated with loss of pain sensation. Cognition and sensation is otherwise normal and there is no detectable physical abnormality. We report a case of Congenital Insensitivity to Pain in a 3 year old female child.
altloc:
  - http://www.ojhas.org/issue36/2010-4-29.htm
chapter: ~
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creators_id:
  - dr_praveenrao@yahoo.co.in
  - ~
  - ~
creators_name:
  - family: B
    given: Praveen Kumar
    honourific: ''
    lineage: ''
  - family: S
    given: Sudhakar
    honourific: ''
    lineage: ''
  - family: MPV
    given: Prabhat
    honourific: ''
    lineage: ''
date: 2011-01-20
date_type: published
datestamp: 2011-05-02 17:14:59
department: ~
dir: disk0/00/00/72/76
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editors_id:
  - BS Kakkilaya
editors_name:
  - family: Kakkilaya
    given: Srinivas
    honourific: Dr
    lineage: ''
eprint_status: archive
eprintid: 7276
fileinfo: /style/images/fileicons/application_pdf.png;/7276/1/2010%2D4%2D29.pdf
full_text_status: public
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keywords: Congenital; Pain; Insensitivity; Nerve; HSAN
lastmod: 2011-05-02 17:14:59
latitude: ~
longitude: ~
metadata_visibility: show
note: ~
number: 4
pagerange: ~
pubdom: TRUE
publication: Online Journal of Health and Allied Sciences
publisher: BS Kakkilaya
refereed: TRUE
referencetext: "1.\tMerskey H, Bogduk N, editors. Classification of chronic pain, Task Force on Taxonomy, International Association for the Study of Pain. 2nd ed. Seattle: IASP Press: 1994. p. 210-213.\r\n2.\tCox JJ et al. An SCN9A channelopathy causes congenital inability to experience pain. Nature. 2006;444:894-898.\r\n3.\tUnknown author. Insensitivity to pain. BMJ 1973;27:187-188.\r\n4.\tNishida G. Congenital Anhidrosis. Saishin Igaku (Japan) 1951;6:1100-1104.\r\n5.\tDrenth JPH, Waxman SG.  Mutations in sodium-channel gene SCN9A cause a spectrum of human genetic pain disorders. J. Clin. Invest 2007;117(12):3603-3609.\r\n6.\tProtheroe SM. Congenital insensitivity to pain. Journal of the Royal Society of Medicine 1991;84:558-559.\r\n7.\tFelicia B, Max J. Inherited Autonomic Neuropathies. Seminars in Neurology 2003;23(4).\r\n8.\tPinsky L, DiGeorge AM. Congenital familial sensory neuropathy with anhidrosis. J Pediatr 1966;68:1-13.\r\n9.\tNational Institute of Neurological Disorders and Stroke: NINDS Lesch-Nyhan Syndrome Information Page. Available at: http://www.ninds.nih.gov/disorders/lesch_nyhan/lesch_nyhan.htm. Accessed February 13, 2007\r\n10.\tMedscape’s Continually Updated Clinical Reference: Lesch-Nyhan Syndrome. Available at: http://emedicine.medscape.com/article/1181356-overview. Accessed Jun 29th, 2010.\r\n11.\tEdwards-Lee TA. Cornford ME, Yu K-T T. Congenital insensitivity to pain and anhidrosis with mitochondrial and axonal abnormalities. Pediatr Neurol 1997;17:356-361. \r\n12.\tSerendip Update's blog: Congenital Insensitivity to Pain with Anhidrosis. Available at: http://serendip.brynmawr.edu/exchange/node/1736. Accessed April 1st, 2008."
relation_type: []
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reportno: ~
rev_number: 18
series: ~
source: ~
status_changed: 2011-05-02 17:14:59
subjects:
  - OJHAS
succeeds: ~
suggestions: ~
sword_depositor: ~
sword_slug: ~
thesistype: ~
title: Congenital Insensitivity to Pain
type: journale
userid: 4338
volume: 9
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