---
abstract: 'Metaplastic breast carcinoma is very rare neoplasm which contains mixture of carcinomatous  (epithelial) and sarcomatous (mesenchymal) elements in variable proportion. Metaplastic carcinoma with chondroid differentiation is even rarer. We report a case of metaplastic carcinoma with extensive chondroid differentiation as there is paucity of information regarding pathological features and clinical outcomes for these rare tumors. Tumor had characteristic definite areas of classic infiltrating duct carcinoma with abundant chondromyxoid matrix, focal areas of chondrosarcoma and cartilagenous  metaplasia. Tumour cells were immunoreactive for S-100, ER, and PR. When pathologist encounter breast tumor with chondroid differentiation, careful gross sampling, histopathology and immunoreactivity for mesenchymal and epithelial component are most useful to differentiate metaplastic carcinoma from malignant phylloides tumors and malignant adenomyoepithelioma.'
altloc:
  - http://www.ojhas.org/issue36/2010-4-30.htm
chapter: ~
commentary: ~
commref: ~
confdates: ~
conference: ~
confloc: ~
contact_email: ~
creators_id:
  - drdhirajnikumbh@rediffmail.com
  - ~
  - ~
  - ~
  - ~
creators_name:
  - family: Nikumbh
    given: Dhiraj B
    honourific: ''
    lineage: ''
  - family: Jagtap
    given: Sunil V
    honourific: ''
    lineage: ''
  - family: Kanetkar
    given: Sujata R
    honourific: ''
    lineage: ''
  - family: Jain
    given: Gaurav
    honourific: ''
    lineage: ''
  - family: Bohra
    given: Ashish
    honourific: ''
    lineage: ''
date: 2011-01-20
date_type: published
datestamp: 2011-05-02 17:14:51
department: ~
dir: disk0/00/00/72/77
edit_lock_since: ~
edit_lock_until: 0
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editors_id:
  - BS Kakkilaya
editors_name:
  - family: Kakkilaya
    given: Srinivas
    honourific: Dr
    lineage: ''
eprint_status: archive
eprintid: 7277
fileinfo: /style/images/fileicons/application_pdf.png;/7277/4/2010%2D4%2D30.pdf
full_text_status: public
importid: ~
institution: ~
isbn: ~
ispublished: pub
issn: ~
item_issues_comment: []
item_issues_count: 0
item_issues_description: []
item_issues_id: []
item_issues_reported_by: []
item_issues_resolved_by: []
item_issues_status: []
item_issues_timestamp: []
item_issues_type: []
keywords: Metaplastic carcinoma; Chondroid differentiation
lastmod: 2011-05-02 17:14:51
latitude: ~
longitude: ~
metadata_visibility: show
note: ~
number: 4
pagerange: ~
pubdom: TRUE
publication: Online Journal of Health and Allied Sciences
publisher: BS Kakkilaya
refereed: TRUE
referencetext: "1.\tRosen PP. Carcinoma with metaplasia.In :Rosen PP,editor.Rosens Breast Pathology. 2nd edition. Philadelphia: Lippincott Williams and Wilkins. 2001. pp 425-452\r\n2.\tTavassoli FA. Papillary lesions.In :Tavassoli FA,editor.Pathology of Breast. 2nd edition. Stanford (CT): Appleton and Lange. 1999. 481-504\r\n3.\tDunne B, Lee AH, Pinder SE et al. An immunohitochemical study of metaplastic spindle cell carcinoma, phyllodes tumour and fibromatosis of breast. Hum Pathology 2003;34:1009–1015\r\n4.\tPollock JM, Green A, Donnell C, Dyess DL, Tucker JA. Metaplastic Breast Carcinoma with Osseous Differentiation: A Case Report Southern Medical Journal February 2006;99(2):168-170. Available at http://journals.lww.com/smajournalonline/fulltext/2006/02000/metaplastic_breast_carcinoma_with_osseous.19.aspx# \r\n5.\tEllios ID, Corneli ssc CJ, Schnitt SJ et al. Tumour of breast. Invasive Breast Carcinoma. In: Tavassoli FA, Devileep, editors. Pathology and Genetics of tumours of breast and female genital organs. Lyon; IARC Press. 2003. pp 37-41\r\n6.\tTavassoli FA. Classification of  Metaplastic Carcinoma of breast. Pathol Annu 1992;27:89-119.\r\n7.\tHavos AG, Lucas JC, Forte FW. Metaplastic  breast carcinoma: Rare form of mammary cancer. NY State J Med 1973;73:1078-1082.\r\n8.\tAl Sayed AD, Elweshi AM, Tulba AM et al. Metaplastic carcinoma of the breast clinical presentation treatment result and prognostic factors. Acta Onchologica. 2006;45:188-195\r\n9.\tWargotz ES, Norris HJ. Metaplastic carcinoma of the breast. I. Matrix producing carcinoma. Hum Pathol 1989;20:628-635\r\n10.\tPark JM, Hum BK, Moon WK, et al. Metaplastic Carcinoma of the breast : Mammographic and sonographic findings. J clinical Ultrasound 2000;28:179-186.\r\n11.\tGunhan BI, Memis A, Ustam EE et al. Metaplastic carcinoma of breast: Clinical, mammographic and sonographic findings with histological correlation. AJR 2002;178:1421-1425.\r\n12.\tPatterson SK, Tworek JA, Ranbidoux MA et al. Metaplastic carcinoma of the breast; Mammographic appearance with pathological correlation. AJR 1997;169:709-712\r\n13.\tGupta S, Gupta V, Aggarwal PN et al. Primary chondrosarcoma of the breast: A case report. Indian Journal of Cancer 2003;40:77-79\r\n14.\tHee JS, Hak HK, Sun MK, et al. Imaging features of metaplastic carcinoma with chondroid differentiation of the breast. AJR 2007;188:691-696"
relation_type: []
relation_uri: []
reportno: ~
rev_number: 31
series: ~
source: ~
status_changed: 2011-05-02 17:14:51
subjects:
  - OJHAS
succeeds: ~
suggestions: ~
sword_depositor: ~
sword_slug: ~
thesistype: ~
title: Metaplastic Carcinoma of the Left Breast with Extensive Chondroid Differentiation
type: journale
userid: 4338
volume: 9
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