@misc{cogprints7322, volume = {1}, number = {2}, month = {April}, author = {Int J Cur Bio Med Sci. Mona Mlika, Zidi-Moaffak Y , Lakhoua Y, Farah F, Kourda N, Ben Abdallah N, Zermani R, Baltagi-Ben Jilani S }, title = {About A Rare Cause Of Primary Hyperparathyroidism}, publisher = {CurrentSciDirect Publications}, year = {2011}, journal = {Int J Cur Bio Med Sci. }, pages = {47--48}, keywords = {Clear cell hyperplasia, hyperparathyroidism, management}, url = {http://cogprints.org/7322/}, abstract = {Introduction: Primary hyperparathyro{\"i}dism is observed in 35 to 44 subjects/ 100000 persons. The increased production of parathyroid hormones is secondary to primary glandular modifications consisting mainly in adenomas. The authors report a clear-cell hyperplasia causing primary hyperparathyroidism. Observation: We report the case of a 25-year-old man who was admitted to explore pathologic fractures of the left arm and a malignant hypercalcaemia. Complementary laboratory tests revealed primary hyperparathyroidism. A multiple endocrine neoplasia was excluded by radiologic examinations. Cervical ultra-sound examination revealed 2 parathyroid adenomas and per-operative exploration showed 3 ? adenomas ?. Microscopic examination of the 4 parathyroid glands specimen concluded to a clear cell hyperplasia. Conclusion: Clear cell hyperplasia is a benign cause of primary hyperparathyroidism. The diagnosis is based upon histologic findings and examination of the 4 glands. } }