title: Human substantia nigra neurons encode unexpected financial rewards creator: Zaghloul, K.A. creator: Blanco, J.A. creator: Weidemann, C.T. creator: McGill, K. creator: Jaggi, J.L. creator: Baltuch, G.H. creator: Kahana, M.J. subject: Cognitive Psychology subject: Psychophysiology description: The brain's sensitivity to unexpected outcomes plays a fundamental role in an organism's ability to adapt and learn new behaviors. Emerging research suggests that midbrain dopaminergic neurons encode these unexpected outcomes. We used microelectrode recordings during deep brain stimulation surgery to study neuronal activity in the human substantia nigra (SN) while patients with Parkinson's disease engaged in a probabilistic learning task motivated by virtual financial rewards. Based on a model of the ... publisher: American Association for the Advancement of date: 2009 type: Journal (Paginated) type: PeerReviewed format: application/pdf identifier: http://cogprints.org/7713/1/ZaghloulEtAl2009.pdf format: application/pdf identifier: http://cogprints.org/7713/6/ZaghloulEtAl2009_sup.pdf identifier: Zaghloul, K.A. and Blanco, J.A. and Weidemann, C.T. and McGill, K. and Jaggi, J.L. and Baltuch, G.H. and Kahana, M.J. (2009) Human substantia nigra neurons encode unexpected financial rewards. [Journal (Paginated)] relation: http://cogprints.org/7713/