creators_name: Zaghloul, K.A. creators_name: Blanco, J.A. creators_name: Weidemann, C.T. creators_name: McGill, K. creators_name: Jaggi, J.L. creators_name: Baltuch, G.H. creators_name: Kahana, M.J. type: journalp datestamp: 2011-12-16 00:10:00 lastmod: 2011-12-16 00:10:00 metadata_visibility: show title: Human substantia nigra neurons encode unexpected financial rewards ispublished: pub subjects: cog-psy subjects: psycphs full_text_status: public abstract: The brain's sensitivity to unexpected outcomes plays a fundamental role in an organism's ability to adapt and learn new behaviors. Emerging research suggests that midbrain dopaminergic neurons encode these unexpected outcomes. We used microelectrode recordings during deep brain stimulation surgery to study neuronal activity in the human substantia nigra (SN) while patients with Parkinson's disease engaged in a probabilistic learning task motivated by virtual financial rewards. Based on a model of the ... date: 2009 date_type: published publication: Science volume: 323 number: 5920 publisher: American Association for the Advancement of pagerange: 1496-1499 refereed: TRUE citation: Zaghloul, K.A. and Blanco, J.A. and Weidemann, C.T. and McGill, K. and Jaggi, J.L. and Baltuch, G.H. and Kahana, M.J. (2009) Human substantia nigra neurons encode unexpected financial rewards. [Journal (Paginated)] document_url: http://cogprints.org/7713/1/ZaghloulEtAl2009.pdf document_url: http://cogprints.org/7713/6/ZaghloulEtAl2009_sup.pdf