creators_name: Read, Heather L
creators_name: Siegel, Ralph M
type: journalp
datestamp: 1998-03-16
lastmod: 2011-03-11 08:53:36
metadata_visibility: show
title: On the origins of aperiodicities in sensory neuron entrainment
ispublished: pub
subjects: neuro-neu
subjects: neuro-physio
full_text_status: public
keywords: sensory, neuron, irregular, synchronous, asynchronous, dynamic, entrainment
abstract: Aperiodic entrainment to rhythmic sensory input was obtained with either a single neuron or an excitatory network model, without addition of a stochastic or "noisy" element. The entrainment properties of primary sensory neurons were well captured by the dynamics of the Hodgkin-Huxley ordinary differential equations with a quiescent resting state or threshold for spike output. The frequency-amplitude parameter space was compressed and aperiodic regimes were small in comparison to those of periodically activated pacemaker like neurons. Transitions between phase-locked and aperiodic entrainment patterns were predictable and determined by the equation dynamics; supporting the contention that some aperiodicities observed ${in}$ ${situ}$ arise from the inherent membrane properties of neurons. When the rhythmically activated neuron was embedded in an excitatory network of Hodgkin-Huxley neurons with heterogeneous synaptic delays, aperiodic entrainment patterns were more frequently encountered and these were associated with asynchronous output from the network. Embedding the rhythmically activated neuron in a network with synaptic delays, greatly reduced the range of entrained spike frequencies. Other biological mechanisms of modifying the entrainment properties and promoting aperiodic entrainment are discussed.
date: 1996
date_type: published
publication: Neuroscience
volume: 75
number: 1
pagerange: 301-314
refereed: FALSE
citation:   Read, Heather L and Siegel, Ralph M  (1996) On the origins of aperiodicities in sensory neuron entrainment.  [Journal (Paginated)]     
document_url: http://cogprints.org/8/1/neurosci96.html