TY - GEN
ID - cogprints8078
UR - http://cogprints.org/8078/
A1 - Robson, Noorzurani
A1 - Bond, A. J.
A1 - Wolff, K.
TI - Salivary nicotine and cotinine concentrations in unstimulated and stimulated saliva
Y1 - 2012/02//
N2 - Salivary nicotine and salivary cotinine is widely used in clinical and epidemiological studies to validate smoking cessation. However, the reported collection for salivary nicotine and salivary cotinine vary by technique and duration. This study investigated the influence of salivary collection by unstimulation and stimulation technique of the concentration of salivary nicotine and salivary cotinine. It was found that unstimulated technique produced the highest salivary nicotine concentration, whereas stimulated technique produced the highest salivary cotinine concentration. The results of this study suggest that it is important to standardise salivary nicotine and cotinine collection technique.
AV - public
KW - Saliva
smoker
nicotine
cotinine
technique
biological marker
oral
verify
passive
tobacco
smoke
flow-rate
clinical-pharmacology
exposure
smoking
absorption
plasma
urine
ER -