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abstract: "In the beginning of the 20th century the groundbreaking work\r\nof Ramon y Cajal firmly established the neuron doctrine, according to which neurons are the basic structural and functional units of the nervous system. Von Weldeyer coined the term “neuron” in 1891, but the huge leap forward in\r\nneuroscience was due to Cajal’s meticulous microscopic observations of brain sections stained with an improved version of Golgi’s la reazione nera (black reaction). The latter improvement of Golgi’s technique made it possible to visualize the arborizations of single neurons that were “colored brownish black even to their finest branchlets, standing out with unsurpassable clarity upon a transparent yellow background. All was sharp as a sketch with Chinese ink”. The high quality of both the visualization of individual nerve cells and the work performed on studying the anatomy of the central nervous system lead Ramon y Cajal to the conclusion that axons output the nervous impulses to the dendrites or the soma of other target neurons."
altloc:
- http://www.bgscb.org/blog/wp-content/uploads/2012/06/BMR-21_Georgiev.pdf
chapter: ~
commentary: ~
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conference: ~
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creators_id: []
creators_name:
- family: Georgiev
given: Danko D.
honourific: ''
lineage: ''
- family: Glazebrook
given: James F.
honourific: ''
lineage: ''
date: 2010-12
date_type: published
datestamp: 2012-11-09 19:51:52
department: ~
dir: disk0/00/00/86/76
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editors_id: []
editors_name:
- family: Chaldakov
given: George N.
honourific: ''
lineage: ''
eprint_status: archive
eprintid: 8676
fileinfo: /8676/1.hassmallThumbnailVersion/Georgiev_Glazebrook_BMR_2010_21_17-23.pdf;/8676/1/Georgiev_Glazebrook_BMR_2010_21_17-23.pdf
full_text_status: public
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isbn: ~
ispublished: pub
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keywords: 'SNARE protein, exocytosis, neurotransmission, mind, brain'
lastmod: 2013-02-18 15:15:23
latitude: ~
longitude: ~
metadata_visibility: show
note: ~
number: ~
pagerange: 17-23
pubdom: TRUE
publication: BioMedical Reviews
publisher: Bulgarian Society for Cell Biology
refereed: TRUE
referencetext: ~
relation_type: []
relation_uri: []
reportno: ~
rev_number: 11
series: ~
source: ~
status_changed: 2012-11-09 19:51:52
subjects:
- bio-phys
- neuro-chem
- neuro-physio
- phil-mind
succeeds: ~
suggestions: ~
sword_depositor: ~
sword_slug: ~
thesistype: ~
title: SNARE proteins as molecular masters of interneuronal communication
type: journalp
userid: 3568
volume: 21