---
abstract: "The subthalamic nucleus (STN), which receives excitatory inputs from the cortex and has direct connections with the inhibitory pathways\r\nof the basal ganglia, is well positioned to efficiently mediate action selection. Here, we use microelectrode recordings captured during\r\ndeep brain stimulation surgery as participants engage in a decision task to examine the role of the human STN in action selection. We\r\ndemonstrate that spiking activity in the STN increases when participants engage in a decision and that the level of spiking activity\r\nincreases with the degree of decision conflict. These data implicate the STN as an important mediator of action selection during decision\r\nprocesses.\r\n"
altloc: []
chapter: ~
commentary: ~
commref: ~
confdates: ~
conference: ~
confloc: ~
contact_email: ~
creators_id: []
creators_name:
- family: Zaghloul
given: K. A.
honourific: ''
lineage: ''
- family: Weidemann
given: Christoph T.
honourific: ''
lineage: ''
- family: Lega
given: B. C.
honourific: ''
lineage: ''
- family: Jaggi
given: J. L.
honourific: ''
lineage: ''
- family: Baltuch
given: G. H.
honourific: ''
lineage: ''
- family: Kahana
given: M. J.
honourific: ''
lineage: ''
date: 2012
date_type: published
datestamp: 2012-11-09 20:00:07
department: ~
dir: disk0/00/00/87/18
edit_lock_since: ~
edit_lock_until: 0
edit_lock_user: ~
editors_id: []
editors_name: []
eprint_status: archive
eprintid: 8718
fileinfo: /8718/1.hassmallThumbnailVersion/ZaghloulEtAl2012.pdf;/8718/1/ZaghloulEtAl2012.pdf
full_text_status: public
importid: ~
institution: ~
isbn: ~
ispublished: pub
issn: ~
item_issues_comment: []
item_issues_count: ~
item_issues_description: []
item_issues_id: []
item_issues_reported_by: []
item_issues_resolved_by: []
item_issues_status: []
item_issues_timestamp: []
item_issues_type: []
keywords: ~
lastmod: 2013-02-18 15:13:12
latitude: ~
longitude: ~
metadata_visibility: show
note: ~
number: ~
pagerange: 2453-2460
pubdom: TRUE
publication: The Journal of Neuroscience
publisher: ~
refereed: TRUE
referencetext: ~
relation_type: []
relation_uri: []
reportno: ~
rev_number: 13
series: ~
source: ~
status_changed: 2012-11-09 20:00:07
subjects:
- behav-neuro-sci
- cog-psy
- comp-neuro-sci
succeeds: ~
suggestions: ~
sword_depositor: ~
sword_slug: ~
thesistype: ~
title: Neuronal Activity in the Human Subthalamic Nucleus Encodes Decision Conflict during Action Selection
type: journalp
userid: 6246
volume: 32