---
abstract: "There have been proposals for REM to have a\r\nfunction of emotional memory consolidation, and also for\r\nREM sleep to be involved in the promotion of attachment\r\nbehaviour. The hormones cortisol and oxytocin, respec-\r\ntively, may be involved in these proposed REM sleep\r\nfunctions. However, there are conflicting reports on whe-\r\nther levels of cortisol differ between sleep stages when\r\ntime since sleep onset (SSO) is controlled, and virtually no\r\nliterature on whether levels of oxytocin differ between\r\nsleep stages. This study thus investigated the changes in\r\nlevels of oxytocin (OT) and cortisol (CT) across the night,\r\nand whether these levels differ between REM and N2 sleep\r\nwhen time SSO is controlled. 20 participants (10 males, 10\r\nfemales, mean age = 20.45, SD = 2.01) were awakened\r\n10 min into REM and N2 sleep periods in the sleep laboratory and gave saliva samples which were assayed for\r\nOT and CT. Levels of OT were relatively constant across\r\nthe night, whereas CT increased significantly. REM and N2\r\ndid not differ significantly neither for OT nor for CT. The\r\nstudy has implications for models of sleep-dependent\r\nmemory consolidation that incorporate the late sleep\r\nincrease in cortisol as a functional component of memory\r\nconsolidation, and also for the medical diagnostic assaying\r\nof OT during sleep.\r\n\r\n"
altloc: []
chapter: ~
commentary: ~
commref: ~
confdates: ~
conference: ~
confloc: ~
contact_email: ~
creators_id: []
creators_name:
  - family: Blagrove
    given: M.
    honourific: ''
    lineage: ''
  - family: Fouquet
    given: N. C.
    honourific: ''
    lineage: ''
  - family: Baird
    given: A. L.
    honourific: ''
    lineage: ''
  - family: Pace-Schott
    given: E. F.
    honourific: ''
    lineage: ''
  - family: Davies
    given: A. C.
    honourific: ''
    lineage: ''
  - family: Neuschaffer
    given: J. L.
    honourific: ''
    lineage: ''
  - family: Henley-Einion
    given: J. A.
    honourific: ''
    lineage: ''
  - family: Weidemann
    given: Christoph T.
    honourific: ''
    lineage: ''
  - family: Thome
    given: J.
    honourific: ''
    lineage: ''
  - family: McNamera
    given: P.
    honourific: ''
    lineage: ''
  - family: Turnbull
    given: O. H.
    honourific: ''
    lineage: ''
date: 2012
date_type: published
datestamp: 2012-11-09 20:00:24
department: ~
dir: disk0/00/00/87/20
edit_lock_since: ~
edit_lock_until: 0
edit_lock_user: ~
editors_id: []
editors_name: []
eprint_status: archive
eprintid: 8720
fileinfo: /8720/1.hassmallThumbnailVersion/BlagroveEtAl2012.pdf;/8720/1/BlagroveEtAl2012.pdf
full_text_status: public
importid: ~
institution: ~
isbn: ~
ispublished: pub
issn: ~
item_issues_comment: []
item_issues_count: ~
item_issues_description: []
item_issues_id: []
item_issues_reported_by: []
item_issues_resolved_by: []
item_issues_status: []
item_issues_timestamp: []
item_issues_type: []
keywords: ~
lastmod: 2013-02-18 15:12:46
latitude: ~
longitude: ~
metadata_visibility: show
note: ~
number: ~
pagerange: 1223-1232
pubdom: TRUE
publication: Journal of Neural Transmission
publisher: ~
refereed: TRUE
referencetext: ~
relation_type: []
relation_uri: []
reportno: ~
rev_number: 13
series: ~
source: ~
status_changed: 2012-11-09 20:00:24
subjects:
  - physio-psy
  - psy-bio
succeeds: ~
suggestions: ~
sword_depositor: ~
sword_slug: ~
thesistype: ~
title: Association of salivary-assessed oxytocin and cortisol levels with time of night and sleep stage
type: journalp
userid: 6246
volume: 119
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