?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Anemia+in+Antiretroviral+Na%C3%AFve+HIV%2FAIDS+Patients%3A+A+Study+from+Eastern+India&rft.creator=Pande%2C+A&rft.creator=Bhattacharyya%2C+M&rft.creator=Pain%2C+S&rft.creator=Ghosh%2C+B&rft.creator=Saha%2C+S&rft.creator=Ghosh%2C+A&rft.creator=Banerjee%2C+A&rft.subject=Online+Journal+of+Health+and+Allied+Sciences&rft.description=Background%3A+Hematological+manifestations+are+common+throughout+the+course+of+HIV+infection.+Impact+of+anemia+is+the+most+significant+among+them.+The+present+study+was+undertaken+to+evaluate+the+etiologies+underlying+anemia+in+HIV%2FAIDS.+Methods+This+was+a+non+randomized+cross+sectional+observational+study+conducted+in+a+tertiary+care+hospital+of+India+over+a+period+of+2+years.+One+hundred+and+fifty+HIV+patients+were+screened.+Thorough+clinical+and+laboratory+evaluation+was+done+in+50+randomly+selected+anemic+cases.+Results%3A+Proper+etiological+diagnosis+could+be+reached+in+46+patients.+Among+them+correlation+between+Hb%25+and+CD4+count+was+statistically+insignificant+(p+%3D+0.074%2C+r+%3D+0.47)+whereas+it+was+significant+with+absolute+lymphocyte+and+CD4+count+(p+%3D+0.006%2C+r+%3D+0.41).+There+was+better+correlation+of+bone+marrow+iron+status+with+percent+saturation+of+transferrin+(p+%3D+0.003%2C+r+%3D+0.54)+than+with+serum+ferritin+(p+%3D+0.055%2C+r+%3D+0.09).+Bone+marrow+iron+status+did+not+have+any+relationship+with+CD4+count.+Anemia+of+chronic+disease+was+the+commonest+etiology+(37%25)+followed+by+HIV+related+myelodysplastic+syndrome+(31%25)%2C+iron+deficiency+anemia+(13%25)%2C+bone+marrow+suppression+due+to+direct+involvement+by+some+infective+process+(7%25).+Aplastic+anemia%2C+multiple+myeloma%2C+Hodgkin%E2%80%99s+disease%2C+pure+red+cell+aplasia%2C+hemophagocytic+lymphohistiocytosis+and+vitamin+B12+deficiency+were+detected+in+one+case+(2%25)+each.+Conclusions%3A+Etiologies+of+anemia+in+HIV%2FAIDS+are+multifactorial+with+anemia+of+chronic+disease+being+the+commonest.+For+screening+of+iron+deficiency+in+this+group%2C+percent+saturation+is+a+better+tool+than+serum+ferritin.+Absolute+lymphocyte+count+can+sometimes+be+used+as+a+surrogate+marker+of+immunological+status+in+antiretroviral+na%C3%AFve+HIV+patients%2C+particularly+in+resource+poor+areas.&rft.publisher=BS+Kakkilaya&rft.contributor=Kakkilaya%2C+Dr+Srinivas&rft.date=2012-01-15&rft.type=Journal+(On-line%2FUnpaginated)&rft.type=PeerReviewed&rft.format=application%2Fpdf&rft.identifier=http%3A%2F%2Fcogprints.org%2F8854%2F1%2F2011-4-4.pdf&rft.identifier=++Pande%2C+A+and+Bhattacharyya%2C+M+and+Pain%2C+S+and+Ghosh%2C+B+and+Saha%2C+S+and+Ghosh%2C+A+and+Banerjee%2C+A++(2012)+Anemia+in+Antiretroviral+Na%C3%AFve+HIV%2FAIDS+Patients%3A+A+Study+from+Eastern+India.++%5BJournal+(On-line%2FUnpaginated)%5D+++++&rft.relation=http%3A%2F%2Fcogprints.org%2F8854%2F