creators_name: Rupani, MP creators_name: Vasava, BC creators_name: Mallick, KH creators_name: Gharat, VV creators_name: Bansal, R creators_id: mihirrupani@yahoo.com editors_name: Kakkilaya, Srinivas editors_id: Kakkilaya BS type: journale datestamp: 2013-05-04 23:05:52 lastmod: 2013-05-04 23:05:52 metadata_visibility: show title: Reaching Community Through School Going Children for Sickle Cell Disease in Zankhvav Village of Surat District, Western India ispublished: pub subjects: OJHAS full_text_status: public keywords: Sickle cell disease; Screening; Tribal; School going children abstract: Objectives: The objective of the study was to explore a method to reach the community via school going adolescents for screening tribal people for Sickle Cell disease. Methodology: A cross-sectional study was conducted in a total of 1023 school going adolescents for Sickle Cell Disease screening by Dithionite Tube Turbidity (DTT) test with subsequent Hemoglobin Electrophoresis for confirmation among those testing positive for DTT. They were then advised to get their family members tested for the same. Results: 24.41% of school going adolescents tested positive by DTT test. 152 family members of those positive school children came forward for testing. On performing the DTT test on the family members, 53.94% tested positive. Out of those who tested positive, 61% belonged to Vasava caste; 36.6% belonged to Chaudhari caste followed by Gamit and Dhodhia Patel. On the subsequent Hemoglobin electrophoresis, 52.63% of the family members were found to be positive for Sickle Cell Trait and 1.97% tested positive for Sickle Cell Disease. Conclusions: School going children can be an effective medium to approach the community for the screening of Sickle Cell Disease. date: 2012-07-25 date_type: published publication: Online Journal of Health and Allied Sciences volume: 11 number: 2(4) publisher: BS Kakkilaya refereed: TRUE referencetext: 1. Health and Family Welfare Department. Govt. of Gujarat. Sickle Cell Anemia Control Program. Available at http://www.gujhealth.gov.in/Portal/Tender/20/1_sickle-cell-anemia-control-programme-add.pdf. Accessed 04-02-2012. 2. Sharma RS. Hemoglobinopathies in Western India. Journal of Association of Physician India 1973;2: 969-973. 3. Patra PK, Chauhan VS, Khodiar PK et al. Screening for the sickle cell gene in Chhattisgarh state, India: an approach to a major public health problem. J Community Genet 2011;2:147–151. 4. Kar BC. Sickle cell disease in India. J Assoc Physicians India. 1991;39:954–960. 5. Lemann H. Sickle Cell Trait in Southern India. BMJ Feb 1952;405. 6. Samal GC, Naik KN. Incidence of sickle-cell disease in school children of western Orissa. Ind J Haematol 1983;1:51–54. 7. Huntsman R C. A rapid whole blood solubility test to differentiate the sickle cell trait from Sickle Cell Anemia. Journal of Clinical Pathology 1970;23:781-783. 8. Saunthararajah Y, Vinchinsky EP. Sickle Cell Disease – Clinical Features and Management. In Hoffman R, Benz Jr. EJ, Shattil S et al.(editors). Hematology: Basic Principles and Practice. 5th ed. Philadelphia: Churchill Livingstone (Elsevier); 2009. pp577-578. 9. World Health Organization. Nutritional Anemias. Technical Report Series No. 405. Geneva; 1968. p9. Available at http://whqlibdoc.who.int/trs/WHO_TRS_405.pdf. Accessed 19-05-2012. 10. Sahu T, Sahani NC, Das S, Sahu SK. Sickle cell anemia in tribal children of Gajapati district in south Orissa. Ind J Comm Med 2003;28:180-183. 11. Balgir RS. The spectrum of hemoglobin variants in two scheduled tribes of Sundargarh district in north-western Orissa, India. Annals of Human Biology 2005;32:560-573. 12. Kamble M, Chatruvedi P. Epidemiology of sickle cell disease in a rural hospital of central India. Indian Pediatr 2000;37:391-396. citation: Rupani, MP and Vasava, BC and Mallick, KH and Gharat, VV and Bansal, R (2012) Reaching Community Through School Going Children for Sickle Cell Disease in Zankhvav Village of Surat District, Western India. [Journal (On-line/Unpaginated)] document_url: http://cogprints.org/8892/1/2012-2-4.pdf