?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Cost+-+utility+analysis+of+parenteral+antibiotics+prescribed+in+medical+wards+in+a+tertiary+care+health+facility+in+southern+province+of+Sri+Lanka.&rft.creator=Hettihewa%2C+LM&rft.creator=Kodikara%2C+T&rft.creator=Manamperi%2C+R&rft.subject=Online+Journal+of+Health+and+Allied+Sciences&rft.description=Introduction%3A+Parenteral+antibiotic+(PA)+prescription+pattern+in+a+hospital+will+directly+influence+the+annual+budget+allocation%2C+development+of+bacterial+resistance+and+occurrence+of+unnecessary+adverse+drug+reactions+if+it+is+done+with+poor+adherence+to+the+standard+guidelines+of+prescription.+As+specialist+in+the+field+we+understand+the+need+of+conducting+economic+studies+in+relation+to+the+cost+and+utility+of+PA+prescription+pattern.+It+will+be+helpful+to+predict+the+drug+procurement+plan+for+the+next+year+and+also+to+prevent+unnecessary+complications+mentioned+above.+Objective%3A+Our+main+objective+was+to+analyze+the+cost%2Futility+relationship+of+PA+drugs+which+were+used+in+medical+wards+in+this+hospital+according+to+the+top+ten+of+the+cost+(TTTC)+and+the+top+ten+of+the+consumption+(TTCS).+Materials+and+method+%3A+Aggregate+data+from+the+pharmacy+record+books+were+collected+for+year+2010+from+indoor+pharmacy.+Unit+prize+was+obtained+from+medical+supplies+division.+Total+quantity+consumed+by+each+medical+ward+was+considered+for+analysis+of+the+cost+%2Futility+relationship.+Two+top+ten+lists+were+prepared+according+to+the+cost+and+the+consumption+respectively+for+medical+wards+and+the+correlation+was+analyzed+using+non+parametric+testing+with+spearman+test.+Results%3A+Regarding+PA+drugs+used+in+this+hospital%2C+7%2F10+PA+drugs+in+TTTC+are+not+included+in+the+TTCS.+Out+of+the+total+cost+for+TTTC%2C+82.6%25+of+the+cost+had+been+spent+for+the+PA+drugs+which+are+not+in+the+TTCS+and+17.5%25+of+the+cost+of+TTTC+was+used+to+purchase+only+three+drugs+from+the+TTCS.+But+these+three+drugs+had+contributed+only+28%25+of+top+ten+consumption.+72%25+of+the+PA+drugs+in+TTCS+were+not+costly+drugs+and+highly+consumed+in+medical+wards.+Correlation+was+significantly+positive+between+cost+and+utility+of+PA+drugs.+(+r%3D-0.91%2Cp%3C0.001)+Conclusion%3A+Majority+of+the+consumed+PA+drugs+are+non-costly+and+it+indicates+the+prescriptions+had+been+done+according+to+the+rational+guidelines+including+cost%2C+availability+and+affordability.+Correlation+further+confirms+that+majority+of+the+PA+consumption+was+low+costly+drugs.+As+most+of+the+money+had+been+spent+to+purchase+highly+expensive+PA+drugs+for+medical+wards+we+suggest+to+review+the+clinical+indications+for+these+drugs+with+the+microbiological+evidence+to+be+compatible+with+the+allocated+health+budget+for+the+hospital.+This+further+suggests+conducting+the+cost+effective+economic+studies+to+evaluate+the+suitable+drug+alternatives+for+such+indications.&rft.publisher=Kakkilaya+BS&rft.contributor=Kakkilaya%2C+Dr+Srinivas&rft.date=2012-10-25&rft.type=Journal+(On-line%2FUnpaginated)&rft.type=PeerReviewed&rft.format=application%2Fpdf&rft.identifier=http%3A%2F%2Fcogprints.org%2F8912%2F1%2F2012-3-2.pdf&rft.identifier=++Hettihewa%2C+LM+and+Kodikara%2C+T+and+Manamperi%2C+R++(2012)+Cost+-+utility+analysis+of+parenteral+antibiotics+prescribed+in+medical+wards+in+a+tertiary+care+health+facility+in+southern+province+of+Sri+Lanka.++%5BJournal+(On-line%2FUnpaginated)%5D+++++&rft.relation=http%3A%2F%2Fcogprints.org%2F8912%2F