creators_name: Kalloli, M creators_name: Vijayakumar, M creators_name: Srinivas, C creators_name: Ramachandra, C creators_id: mahesh.kalloli@gmail.com editors_name: Kakkilaya, Srinivas editors_id: Kakkilaya BS type: journale datestamp: 2013-05-04 23:08:30 lastmod: 2013-05-04 23:08:30 metadata_visibility: show title: A Rare Giant Pleural Thymoma in Posterior Mediastinum. ispublished: pub subjects: OJHAS full_text_status: public keywords: Thymoma; Pleural tumor; Posterior mediastinum; Surgical excision abstract: Thymoma is an epithelial neoplasm of the thymus, which commonly lies in the anterior mediastinum. Unusually, thymomas can also be found in other locations. Surgical excision, when feasible, appears to provide good results. We encountered a rare case of a thymoma that developed in the right thoracic cavity, and originating from the pleura in posterior mediastinum. We describe the clinical scenario, investigations, and our management of the patient. date: 2012-10-25 date_type: published publication: Online Journal of Health and Allied Sciences volume: 11 number: 3(9) publisher: Kakkilaya BS refereed: TRUE referencetext: 1. Detterbeck FC, Parsons AM. Thymic tumors. Ann Thorac Surg 2004;77:1860–1869. 2. Minniti S, Valentini M, Pinali L, Malago R, Lestani M, Procacci C. Thymic masses of the middle mediastinum: report of 2 cases and review of the literature. J Thorac Imag 2004;19:192–195. 3. Moran CA, Travis WD, Rosado-de-Christenson M, Koss MN, Rosai J. Thymomas presenting as pleural tumors: report of eight cases. Am J Surg Pathol 1992;16:138-144. 4. Johnson SB, Eng TY, Giaccone G, Thomas CR Jr. Thymoma: update for the new millenium. Oncologist. 2001;6:239-246. 5. Kushihashi T, Fujisawa H, Munechika H. Magnetic resonance imaging of thymic epithelial tumors. Crit Rev Diagn Imag 1996;37:191–259. 6. Smith WF, DeWall RA, Krumholz RA. Giant thymoma. Chest. 1970;58:383-384. 7. Masaoka A, Monden Y, Nakahara K, Tanioka T. Follow-up study of thymomas with special reference to their clinical stages. Cancer. 1981;48:2485-2492. 8. Alexiev BA, Drachenberg CB, Burke AP. Thymomas: a cytological and immunohistochemical study, with emphasis on lymphoid and neuroendocrine markers. Diagn Pathol. 2007;11(2):13. doi: 10.1186/1746-1596-2-13. 9. Shin DM, Walsh GL, Komaki R, et al. A multidisciplinary approach to therapy for unresectable malignant thymoma. Ann Intern Med. 1998;129:100-104. 10. Wright CD, Fidias P, Choi NC, Shepard JA, Hasserjian RP. Case records of the Massachusetts General Hospital. Case 16-2007. A 61-year-old man with a mediastinal mass. N Engl J Med. 2007;356(21):2185-2193. 11. Kim ES, Putnam JB, Komaki R, et al. Phase II study of a multidisciplinary approach with induction chemotherapy, followed by surgical resection, radiation therapy, and consolidation chemotherapy for unresectable malignant thymomas: final report. Lung Cancer. 2004;44:369-379. 12. Higashiyama M, Doi O, Kodama K, Yokouchi H. Intrathoracic chemothermotherapy following panpleuropneumonectomy for pleural dissemination of invasive thymoma. Chest. 1994;105:1884-1885. 13. Palmieri G, Lastoria S, Colao A, et al. Successful treatment of a patient with a thymoma and pure red-cell aplasia with octreotide and prednisone. N Engl J Med. 1997;336:263-265. 14. Iwasaki Y, Ohsugi S, Takemura Y, et al. Multidisciplinary therapy including high-dose chemotherapy followed by peripheral blood stem cell transplantation for invasive thymoma. Chest. 2002;122:2249-2252. citation: Kalloli, M and Vijayakumar, M and Srinivas, C and Ramachandra, C (2012) A Rare Giant Pleural Thymoma in Posterior Mediastinum. [Journal (On-line/Unpaginated)] document_url: http://cogprints.org/8919/1/2012-3-9.pdf