creators_name: Ravikumar, HN creators_name: Vani, R creators_name: Santosh, KV creators_name: Joji, A creators_id: drravikumar@metropolisindia.com editors_name: Kakkilaya, Srinivas editors_id: Kakkilaya BS type: journale datestamp: 2013-05-04 23:08:39 lastmod: 2013-05-04 23:08:39 metadata_visibility: show title: Retinal Dysplasia Mimicking Retinoblastoma. ispublished: pub subjects: OJHAS full_text_status: public keywords: Retinal Dysplasia; Retinoblastoma; Leukocoria abstract: Retinal dysplasia represents a congenital disorder characterized by abnormal proliferation of retinal tissue causing leukocoria. We present a case of an infant with bilateral leukocoria, clinically diagnosed as retinoblastoma, followed by enucleation of the left eye. Microscopy however, demonstrated retinal dysplasia consisting of a disorderly proliferation of retinal tissue with formation of rosettes, mimicking retinoblastoma. Microscopic features that aid in differentiating this lesion from retinoblastoma are discussed. date: 2012-10-25 date_type: published publication: Online Journal of Health and Allied Sciences volume: 11 number: 3(10) publisher: BS Kakkilaya refereed: TRUE referencetext: 1. Reese AB, Blodi FC: Retinal dysplasia. Am J Ophthalmol 1950;33:23. 2. Chan A, Lakshminrusimha S, Heffner R, Gonzalez-Fernandez F. Histogenesis of retinal dysplasia in trisomy 13. Diagn Pathol. 2007;2:48. 3. de Graaf P, van der Valk P, Moll AC, Imhof SM, Schouten-van Meeteren AY, Castelijns JA. Retinal dysplasia mimicking intraocular tumor: MR imaging findings with histopathologic correlation. AJNR Am J Neuroradiol.2007;28(9):1731-1733. 4. Lloyd IC, Colley A, Tullo AB, Bonshek R. Dominantly inherited unilateral retinal dysplasia. Br J Ophthalmol. 1993;77(6):378-80. 5. Agarwal N, Gupta P, Agarwal A, Pantola C. Retinal Dysplasia – A Mimic of Malignant Ocular Pathology. J of Clinical and Diagnostic Research. 2011:5(2);367-368. 6. Gonzalez-Fernandez F, Lopes MB, Garcia-Fernandez JM, Foster RG, De Grip WJ, Rosemberg S, Newman SA, VandenBerg SR. Expression of developmentally defined retinal phenotypes in the histogenesis of retinoblastoma. Am J Pathol. 1992;141(2):363-375. 7. Eagle EC. Ch 11, Retinoblastoma and other pediatric intraocular tumors. In Eye Pathology – An Atlas and Basic Text. W.B. Saunders Co., Philadelphia. 1999. p. 199-205. citation: Ravikumar, HN and Vani, R and Santosh, KV and Joji, A (2012) Retinal Dysplasia Mimicking Retinoblastoma. [Journal (On-line/Unpaginated)] document_url: http://cogprints.org/8920/1/2012-3-10.pdf