?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=The+Association+of+Antidepressant+Medication+and+Body+Weight+Gain&rft.creator=Ranjbar%2C+Sara&rft.creator=Pai%2C+Nagesh+Brahmavar&rft.creator=Deng%2C+Chao&rft.subject=Online+Journal+of+Health+and+Allied+Sciences&rft.subject=Neuropharmacology&rft.description=Objective%3A+To+review+the+literature+and+discover+which+antidepressants+are+responsible+for+weight+gain+and+then+to+discuss+the+areas+with+lack+of+adequate+knowledge.+Method%3A+An+electronic+search+was+conducted+through+Medline%2C+Pubmed%2C+Cochrane+library%2C+and+ScienceDirect.+Forty+nine+empirical+researches+were+identified+and+reviewed.+Results%3A+Amitriptyline%2C+clomipramine%2C+and+mirtazapine+have+been+associated+with+more+weight+gain+induction+in+clinical+studies%2C+but+not+in+animal-based+studies.+All+TCAs+have+been+reported+to+cause+weight+gain+except+protriptyline.+MAOIs+have+been+associated+with+weight+gain.+In+SSRI+group%2C+citalopram+and+ecitalopram+induce+weight%2C+yet+mixed+results+exist+for+paroxetine+and+fluoxetine.+Researches+unanimously+reported+weight+loss+effect+for+bupropion.+Some+studies+suggest+contributing+factors+in+the+relationship+of+antidepressants+with+body+weight+changes+including+age%2C+gender%2C+base-line+weights+and+treatment+duration.+Various+results+of+different+treatment+durations+have+been+reported+in+some+cases+but+there+are+not+continuous+time-dependent+studies+for+the+influences+of+antidepressants+on+body+weight+changes.+Conclusion%3A+More+studies+are+required+to+discover+underlying+mechanisms+and+the+time-dependent+effects+of+antidepressants+on+body+weight+changes.&rft.publisher=Kakkilaya+BS&rft.contributor=Kakkilaya%2C+Dr+Srinivas&rft.date=2013-04-15&rft.type=Journal+(On-line%2FUnpaginated)&rft.type=PeerReviewed&rft.format=application%2Fpdf&rft.identifier=http%3A%2F%2Fcogprints.org%2F9135%2F1%2F2013-1-1.pdf&rft.identifier=++Ranjbar%2C+Sara+and+Pai%2C+Nagesh+Brahmavar+and+Deng%2C+Chao++(2013)+The+Association+of+Antidepressant+Medication+and+Body+Weight+Gain.++%5BJournal+(On-line%2FUnpaginated)%5D+++++&rft.relation=http%3A%2F%2Fcogprints.org%2F9135%2F