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TY - GEN ID - cogprints9649 UR - http://cogprints.org/9649/ A1 - Tan, Prof. Dr. Uner A1 - Tamam, Prof. Dr. Yusuf A1 - Karaca, Prof. Dr. Sibel A1 - Tan, Prof. Dr. Meliha Y1 - 2012/// N2 - Uner Tan syndrome, discovered in 2005 by Dr. Tan, in Southern Turkey, mainly consists of habitual quadrupedal locomotioni impaired intelligence, and dysarthric or no speech, with or without (rarely) cerebello-vermial hypoplasia and mildly simplified cortical gyri. This syndrome may be considered wthin the framework of the nonprogressive autosomal recessive cerebellar ataxias, associated with various genetic mutations (genetic heterogeneity). This is a unique condition among disequilibrium syndrome, Cayman ataxia, and Joubert syndrome. From the viewpoint of dynamical systems theory, there may be not a single factor including a ganetic code that predetermines the emergence of human qu?adrupedalism, seen for instance in Uner Tan syndrome. Rather it may involve self-organization process, consisting of many decentralized and local interactions among neuronal, genetic, and environmental subsystems. PB - InTech Publications KW - Uner Tan syndrome KW - human quadrupedalism KW - locomotion KW - ataxia KW - speech KW - intelligence KW - cerebellum KW - systems theory KW - self-organization KW - evolution TI - Uner Tan Syndrome: Review and Emergence of Human Quadrupedalism in Self-Organization, Attarctors and evolutionary Perspectives SP - 1 AV - public EP - 44 ER -