%A Prof. Dr. Uner Tan
%A Prof. Dr.  Yusuf Tamam
%A Prof. Dr. Sibel Karaca
%A Prof. Dr.  Meliha Tan
%J InTech, Rijeka, Croatia
%T Uner Tan Syndrome: Review and Emergence of Human Quadrupedalism in Self-Organization, Attarctors and evolutionary Perspectives
%X Uner Tan syndrome, discovered in 2005 by Dr. Tan, in Southern Turkey, mainly consists of habitual quadrupedal locomotioni impaired intelligence, and dysarthric or no speech, with or without (rarely) cerebello-vermial hypoplasia and mildly simplified cortical gyri. 
This syndrome may be considered wthin the framework of the nonprogressive autosomal recessive cerebellar ataxias, associated with various genetic mutations (genetic heterogeneity). This is a unique condition among disequilibrium syndrome, Cayman ataxia, and Joubert syndrome. 
From the viewpoint of dynamical systems theory, there may be not a single factor including a ganetic code that predetermines the emergence of human qu?adrupedalism, seen for instance in Uner Tan syndrome. Rather it may involve self-organization process, consisting of many decentralized and local interactions among neuronal, genetic, and environmental subsystems. 
%K Uner Tan syndrome, human quadrupedalism, locomotion, ataxia, speech, intelligence, cerebellum, systems theory, self-organization, evolution
%P 1-44
%E Prof. Dr.  Uner Tan
%D 2012
%I InTech Publications
%L cogprints9649

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