--- abstract: "Sister Mary Joseph's nodule (SMJN) is an eponym used to describe the metastatic lesion of the umbilicus. Umbilical metastases are rare and its occurrence as a first manifestation of an asymptomatic primary malignancy is very rare. The gallbladder is the source of SMJN in 2%-3% of cases. SMJN can present in any one of the following ways; first manifestation of an occult primary malignancy, an indication of recurrence in a patient with a previous malignancy, or as progression of an underlying symptomatic primary disease. Our study emphasizes the importance of identifying this very useful and easily applicable clinical sign by careful physical examination of the abdomen, and also the need for proper clinical evaluation of any umbilical lesion, and the histological diagnosis. In the present study we report on a case of Sister Mary Joseph's Nodule as the presentation of an asymptomatic gallbladder carcinoma, and review the relevant literature." altloc: - http://www.ojhas.org/issue49/2014-1-7.html chapter: ~ commentary: ~ commref: ~ confdates: ~ conference: ~ confloc: ~ contact_email: ~ creators_id: [] creators_name: - family: Pampanagouda given: SKM honourific: '' lineage: '' - family: Suryadevara given: S honourific: '' lineage: '' - family: Kumar given: V honourific: '' lineage: '' - family: Deshmane given: V honourific: '' lineage: '' - family: Mukunda given: M honourific: '' lineage: '' date: 2014-05-15 date_type: published datestamp: 2016-07-11 15:45:23 department: ~ dir: disk0/00/00/97/33 edit_lock_since: ~ edit_lock_until: 0 edit_lock_user: ~ editors_id: - Kakkilaya BS editors_name: - family: Kakkilaya given: Srinivas honourific: Dr lineage: '' eprint_status: archive eprintid: 9733 fileinfo: /style/images/fileicons/application_pdf.png;/9733/1/2014-1-7.pdf full_text_status: public importid: ~ institution: ~ isbn: ~ ispublished: pub issn: ~ item_issues_comment: [] item_issues_count: ~ item_issues_description: [] item_issues_id: [] item_issues_reported_by: [] item_issues_resolved_by: [] item_issues_status: [] item_issues_timestamp: [] item_issues_type: [] keywords: Sister Mary Joseph's Nodule (SMJN); Umbilicus mass; Gall bladder carcinoma lastmod: 2016-07-11 15:45:23 latitude: ~ longitude: ~ metadata_visibility: show note: ~ number: 1 pagerange: ~ pubdom: TRUE publication: Online Journal of Health and Allied Sciences publisher: Kakkilaya BS refereed: TRUE referencetext: "1.\tWalshe WH. The nature and treatment of cancer. The British and Foreign medical review. 1846:293-311.\r\n2.\tMayo WJ. Metastases in cancer. Proceedings of the Staff Meetings of the Mayo Clinic 1928;3:327.\r\n3.\tBailey H. Demonstration of Physical Signs in Clinical Surgery, 11th edition. Baltimore, Williams and Wilkins, 1949, pp 227.\r\n4.\tSrinivasan R. Metastatic cutaneous and subcutaneous deposits from internal carcinoma. An analysis of cases diagnosed by fine needle aspiration. Acta Cytol. 1993;37:894-898.\r\n5.\tPapala JA, Selim MA. Metastatic vs primary malignant neoplasms affecting the umbilicus: clinicopathologic features of 77 tumors. Annals of Diagnostic Pathology.2011;15:237-242.\r\n6.\tLookingbill D, Spangler N, Sexton FM. Skin involvement as the presenting sign of internal carcinoma. A retrospective study of 7316 cancer patients. J Am Acad Dermatol 1990;22:19-26.\r\n7.\tFalchi M, Cecchini G, Derchi LE. Umbilical metastasis as first sign of cecal carcinoma in a cirrhotic patient (Sister Mary Joseph nodule). Report of a case [Italian] Radiol Med. 1999;98:94-96.\r\n8.\tGabriele R, Conte M, Egidi F, Borghese M. Umbilical metastases: current view point. World J Surg Oncol. 2005;3:13." relation_type: [] relation_uri: [] reportno: ~ rev_number: 9 series: ~ source: ~ status_changed: 2016-07-11 15:45:23 subjects: - OJHAS succeeds: ~ suggestions: ~ sword_depositor: ~ sword_slug: ~ thesistype: ~ title: Umbilical Metastasis as the Manifestation of an Asymptomatic Gallbladder Carcinoma type: journale userid: 4338 volume: 13