Cogprints

Risk Factors for Invasive Epithelial Ovarian Cancer by Histologic Subtype

Thomas Quirk, Jeffrey and Nachimuthu, Natarajan and James Mettlin, Curtis and Barbara Moysich, Kirsten and Swede, Helen (2004) Risk Factors for Invasive Epithelial Ovarian Cancer by Histologic Subtype. [Journal (On-line/Unpaginated)]

Full text available as:

[img]
Preview
PDF
142Kb

Abstract

It is unclear whether the different histologic subtypes of epithelial ovarian carcinoma have different risk factors. We investigated the relationships between selected epidemiologic variables (i.e., parity, family history of ovarian cancer, oral contraceptive use, a history of tubal ligation and noncontraceptive estrogen use) and the major histologic subtypes of epithelial ovarian cancer in a hospital-based case-control study of adult women at Roswell Park Cancer Institute in Buffalo, NY, USA. Multivariate unconditional logistic regression models were used for statistical analysis. We observed a pattern of increased risk associated with family history and a pattern of risk reduction associated with parity, noncontraceptive estrogen use and tubal ligation across all histologic subtype groups. However, we did not observe a consistent pattern of risk associated with oral contraceptive use. These results provide some additional support for the hypothesis that the effects of various ovarian cancer risk factors may differ according to the histologic subtype.

Item Type:Journal (On-line/Unpaginated)
Keywords:Epithelial ovarian cancer, Histology, Epidemiology, Case-control study
Subjects:JOURNALS > Online Journal of Health and Allied Sciences
ID Code:3898
Deposited By: Kakkilaya Bevinje, Dr. Srinivas
Deposited On:22 Oct 2004
Last Modified:11 Mar 2011 08:55

References in Article

Select the SEEK icon to attempt to find the referenced article. If it does not appear to be in cogprints you will be forwarded to the paracite service. Poorly formated references will probably not work.

1.Parkin DM, Pisani P. Ferlay J. Global cancer statistics. CA Cancer J Clin 1999; 49:33-64.

2.Scully RE, Young RH, Clement PB. Atlas of Tumor Pathology, Third Series, Fascicle 23: Tumors of the Ovary, Maldeveloped Gonads, Fallopian Tube, and Broad Ligament. Washington, DC: Armed Forces Institute of Pathology, 1998.

3.Auersperg N, Wong AS, Choi KC, et al. Ovarian surface epithelium: biology, endocrinology, and pathology. Endocr Rev 2001;22: 255-88.

4.Weiss NS, Cook LS, Farrow DC, et al. Ovarian cancer. In: Schottenfeld D, Fraumeni JF Jr, editors. Cancer Epidemiology and Prevention, 2nd ed. New York: Oxford; 1996. p. 1040-57.

5.Troisi R, Hartge P. Ovarian cancer. In: Goldman MB, Hatch MC, editors. Women and Health. San Diego: Academic Press; 2000. p. 907-15.

6.Risch HA, Marrett LD, Jain M, et al. Differences in risk factors for epithelial ovarian cancer by histologic type. Results of a case-control study. Am J Epidemiol 1996;144:363-72.

7.Marchbanks PA, Wilson H, Bastos E, et al. Cigarette smoking and epithelial ovarian cancer by histologic type. Obstet Gynecol 2000; 95: 255-60.

8.Whiteman DC, Murphy MF, Cook LS et al. Multiple births and risk of epithelial ovarian cancer. J Natl Cancer Inst 2000; 92: 1172-7.

9.Titus-Ernstoff L, Perez K, Cramer DW, et al. Menstrual and reproductive factors in relation to ovarian cancer risk. Br J Cancer 2001; 84: 714-21.

10.Purdie DM, Webb PM, Siskind V, et al. The different etiologies of mucinous and nonmucinous epithelial ovarian cancers. Gynecol Oncol 2003;88:S145-8.

11.Parazzini F, Chiaffarino F, Negri E, et al. Risk factors for different histological types of ovarian cancer. Int J Gynecol Cancer 2004;14:431-6.

12.Wittenberg J, Cook LS, Rossing MA, et al. Reproductive risk factors for mucinous and non-mucinous epithelial ovarian cancer. Epidemiology 1999;10:761-3.

13.Modugno F, Ness RB, Wheeler JE. Reproductive risk factors for epithelial ovarian cancer according to histologic type and invasiveness. Ann Epidemiol 2001;11:568-74.

14.Mettlin C. Milk drinking, other beverage habits, and lung cancer risk. Int J Cancer 1989; 43: 608-12.

15.Moysich KB, Mettlin C, Piver MS, et al. Regular use of analgesic drugs and ovarian cancer risk. Cancer Epidemiol Biomarkers Prev 2001;10:903-6.

16.Percy C, van Holten V, Muir C, editors. International Classification of Diseases for Oncology, 2nd ed. Geneva: World Health Organization, 1990.

17.Breslow NE, Day NE. Statistical Methods in Cancer Research, Vol. 1: The Analysis of Case-Control Studies. Lyon: International Agency for Research on Cancer, 1980.

18.Hosmer DW, Lemeshow S. Applied Logistic Regression, 2nd ed. New York: Wiley, 2000.

19.Harlap S. The epidemiology of ovarian cancer. In: Markman M, Hoskins WJ, editors. Cancer of the Ovary. New York: Raven Press; 1993: p. 79-93.

20.Daly M, Obrams GI. Epidemiology and risk assessment for ovarian cancer. Semin Oncol 1998; 25: 255-64.

21.Hankinson SE, Colditz GA, Hunter DJ et al. A prospective study of reproductive factors and risk of epithelial ovarian cancer. Cancer 1995;76:284-90.

22.Wheeler JE. Pathology of malignant ovarian epithelial tumors and miscellaneous and rare ovarian and paraovarian neoplasms. In: Rubin SC, Sutton GP, editors. Ovarian Cancer, 2nd ed. Philadelphia: Lippincott Williams & Wilkins; 2001. p. 99-134.

Metadata

Repository Staff Only: item control page