Cogprints

Role of RBC labeled 99m-Tc scan, Histopathology and Immunohistochemistry in Diagnosis of Jejunal Gastrointestinal Stromal Tumor presenting as obscure gastrointestinal haemorrhage

Shetty, Prasad K and Baliga, Sameer V and K, Balaiah and S, Gnana Prakash (2010) Role of RBC labeled 99m-Tc scan, Histopathology and Immunohistochemistry in Diagnosis of Jejunal Gastrointestinal Stromal Tumor presenting as obscure gastrointestinal haemorrhage. [Journal (On-line/Unpaginated)]

Full text available as:

[img]
Preview
PDF - Published Version
Available under License Creative Commons Attribution No Derivatives.

264Kb

Abstract

Gastrointestinal stromal tumors (GIST) are relatively rare tumors of gastrointestinal (GI) tract, most commonly arise from the stomach followed by small intestine and colon, clinically GIST present with occult GI bleeding, abdominal pain and intestinal obstruction. We present a case of a jejunal GIST, which presented as an obscure GI haemorrhage. This case highlights how oesophagogastrodudenectomy and colonoscopy proved inconclusive in determining source of bleeding and the importance of RBC labeled 99m-Tc scan in detecting the source of GI bleeding and also emphasizes on histopathology and immunohistochemistry in diagnosis of GIST

Item Type:Journal (On-line/Unpaginated)
Keywords:Gastrointestinal stromal tumor; RBC labeled 99m-Tc scan; Immunohistochemistry
Subjects:JOURNALS > Online Journal of Health and Allied Sciences
ID Code:7122
Deposited By: Kakkilaya Bevinje, Dr. Srinivas
Deposited On:22 Nov 2010 14:19
Last Modified:11 Mar 2011 08:57

References in Article

Select the SEEK icon to attempt to find the referenced article. If it does not appear to be in cogprints you will be forwarded to the paracite service. Poorly formated references will probably not work.

1. Miettinen M, Lasota J. Gastrointestinal stromal tumours-definition, clinical, histological, immunohistochemical, and molecular genetic features and differential diagnosis. Virchows Arch 2001 Jan;438(1):1-12.

2. Spiller RC, Parkins RA. Recurrent gastrointestinal bleeding of obscure origin: report of 17 cases and a guide to logical management. Br J Surg 1983 Aug;70(8):489-493.

3. Fox VL. Gastrointestinal bleeding in infancy and childhood. Gastroenterol Clin North Am 2000;29:37–66.

4. Suster S. Gastrointestinal stromal tumors: Radiologic Features with Pathologic Correlation. Semin Diagn Pathol 1996;13:297-313.

5. Mucciarini C, Rossi G, Bertolini F, Valli R, Cirilli C, Rashid I et al. Incidence and clinicopathologic features of gastrointestinal stromal tumours. A population-based study. BMC Cancer 2007;7:230.

6. Hadithi M, Heine GD, Jacobs MA, Van Bodegraven AA, Mulder CJ. A prospective study comparing video capsule endoscopy with double balloon enteroscopy in patients with obscure gastrointestinal bleeding. Am J Gatroenterol 2006;101:52–57.

7. Connolly EM, Gaffney E, Reynolds JV. Gastrointestinal stromal tumors. Br. J Surg 2003;90:1178- 1186.

8. Graadt van Roggen JF, van Velthuysen MLF Hogendoorn PC. The histopathological differential diagnosis of gastrointestinal stromal tumors. J Clin Pathol 2001;54:96- 102.

9. Sircar K, Hewlett BR, Huizinga JD, Chorneyko K, Berezin I, Riddel RH. Interstitial cells of Cajal as precursors of gastrointestinal stromal tumors. AM J Surg Pathol 1999;23:377- 389.

10. Amin MB, Ma CK, Linden MD, Kubus JJ, Zarbo RJ. Prognostic value of proliferating cell nuclear antigen index in gastric stromal tumors. Correlation with mitotic count and clinical outcome. Am J Clin Pathol 1993;100:428-32.

11. Suster S, Sorace D, Moran CA. Gastrointestinal stromal tumors with prominent myxoid matrix. Clinicopathologic, immunohistochemical, and ultrastructural study of nine cases of a distinctive morphologic variant of myogenic stromal tumor. Am J Surg Pathol 1995;19:59-70.

12. Saul SH, Rast ML, Brooks JJ. The immunohistochemistry of gastrointestinal stromal tumors. Evidence supporting an origin from smooth muscle. Am J Surg Pathol 1987;11:464-473.

Metadata

Repository Staff Only: item control page