Cogprints

Health Care Challenges of Hereditary Common Hematological Disorders in Odisha, India

Balgir, RS (2012) Health Care Challenges of Hereditary Common Hematological Disorders in Odisha, India. [Journal (On-line/Unpaginated)]

Full text available as:

[img]
Preview
PDF - Published Version
Available under License Creative Commons Attribution No Derivatives.

239Kb

Abstract

Medical Genetics over the past few decades have emerged as an important and powerful medical specialty with increasing appreciation of its role and function in the biomedical sciences. This emergence is related to a great extent to the progress in the Human Genome Project, which promises wide-ranging applications in the diagnosis, treatment and prevention of human diseases. Nevertheless, the discussion on the role of genetics as the preventive medicine and public health care also lead to ethical, legal and social concerns about general applicability of genetic testing in the ethnic communities. The interpretation of prevention in the context of genetic diseases leads to the unavoidable discussions of genetic engineering, stem cell transplantation, prenatal diagnosis and selective termination of pregnancy, as well as broader concerns about discrimination in health care coverage, gender bias, employment and insurance in the society. In Indian communities where consanguineous marriage is widely practiced, recessive/x-linked genetic disorders such as sickle cell disease and beta-thalassemia, will continue to gain greater prominence in the overall spectrum of ill health. Developing an understanding of these changes will require a wide-ranging and multidisciplinary investigative approach for which public health genetics is ideally suited to conditions in Odisha.

Item Type:Journal (On-line/Unpaginated)
Keywords:Medical Genetics; Sickle Cell Disease; b-Thalassemia; G6PD Deficiency; Public Health Burden; Odisha.
Subjects:JOURNALS
JOURNALS > Online Journal of Health and Allied Sciences
ID Code:8865
Deposited By: Kakkilaya Bevinje, Dr. Srinivas
Deposited On:04 May 2013 23:04
Last Modified:04 May 2013 23:04

References in Article

Select the SEEK icon to attempt to find the referenced article. If it does not appear to be in cogprints you will be forwarded to the paracite service. Poorly formated references will probably not work.

1. Balgir RS. Serogenetc studies in the Gypsy Sikligars of North-western India. Hum Biol 1986;58:171-187.

2. Balgir RS. The spectrum of hemoglobin variants in two scheduled tribes of Sundargarh district in North-western Orissa, India. Ann Hum Biol 2005;32:560-573.

3. Balgir RS. A Genetic study of six typical families of the sickle cell disease in India. Int J Child Health Hum Develop 2010;3:139-149.

4. Balgir RS. Detrimental intrinsic factors contain population explosion for sustainable development in 18 indigenous communities of Orissa, India. In: Pati RN, Jain Atul Kumar (Eds). Biodiversity and Sustainable Development. New Delhi: Swarup Book Publishers Private Limited 2010; pp. 507-516.

5. Balgir RS. Medical genetics in public health administration in India: A handicap of bureaucracy, bias and corruption. Health Administrator (Theme: Health of the Educational Systems) 2005;17:101-109.

6. Balgir RS. Phenotypic diversity of sickle cell disorders with special emphasis on public health genetics in India. Curr Sci 2010;98:1096-1102.

7. Balgir RS. Human genetics in community health practice in India: An urgent need of action. In: Sharma K, Pathak RK, Mehta S and Talwar I (Eds.). Genes, Environment and Health: Anthropological Perspectives. New Delhi: Serials Publications 2007; pp.171-186.

8. Balgir RS. Understanding hemolytic intrinsic health problems in aboriginal communities of Orissa, India: A hindrance for development. Int Res J Social Sci 2009;2:23-33.

9. Balgir RS. Impact of gender bias on health and nutrition of the tribal women in relation to dynamics of development in India. Internet J Biol Anthropol 2009;3:1-11.

10. Balgir RS. Tribal health problems, disease burden and ameliorative challenges in the tribal communities of Eastern Ghats with special reference to Orissa. In: Sarkar RM (Ed.) Primitive Tribal Groups in India: Tradition, Development and Transformation. New Delhi: Serials Publications 2008; pp.273-295.

11. Balgir RS. Biomedical anthropology in contemporary tribal society of India. In: Contemporary Society: Tribal Studies (Tribal Situation in India). Vol.6. Behera, Deepak Kumar, Pfeffer, Georg (Eds). New Delhi: Concept Publishing Company 2005; pp. 292-301.

12. Kar BC, Kulozik AE, Sirr S, Satapathy RK, Kulozik M, Serjeant BE, Serjeant GR. Sickle cell disease in Orissa state, India. Lancet 1986;2:1198-1201.

13. Kar BC, Devi S, Dash KC, Das M. The sickle cell gene is widespread in India. Trans Royal Soc Trop Med Hyg 1987;81:273-275.

14. Kar BC. Sickle cell disease in India. JAPI 1991;39:954-960.

15. Balgir RS. Genetic burden of red cell enzyme glucose-6-phosphate dehydrogenase deficiency in two major scheduled tribes of Sundargarh district in Northwestern Orissa. Curr Sci 2006;92:768-774.

16. Praharaj KC, Mohanta KD, Kar RS, Swain U, Nanda BK. Hemoglobinopathy in Orissa. Indian Pediat 1969;6:533-537.

17. Samal GC, Ahmed B, Behera SK. Incidence of sickle cell disease. Pediat Clin India. 1978;13:33-36.

18. Samal GC, Naik KN. Incidence of sickle cell disease in school children of western Orissa. Indian J Hemat 1983;1:51-54.

19. Balgir RS. Spectrum of hemoglobinopathies in the state of Orissa, India: A ten years cohort study. JAPI 2005;53:1021-1026.

20. Balgir RS. Scenario of hemoglobin variants in Central-East coast of India. Curr Sci 2006;90:1651-1657.

21. Balgir RS. Control and prevention of genetic load of hemoglobinopathies in India. Nat Med J India 1999;12:234-238.

22. Balgir RS. Challenges of imparting IEC for prevention of hereditary sickle cell disorders, b-thalassemia syndrome and G6PD deficiency in India. Tribal Health Bull 2007;13:14-22.

23. Balgir RS. Prevention of hereditary disorders in India: sickle cell disease, b-thalassemia and G6PD deficiency (in English & Oriya). Bhubaneswar: RMRC (ICMR) 2001; pp. 1-12.

24. Balgir RS. Hematological profile of twenty-nine tribal compound cases of hemoglobin-pathies and G6PD deficiency in rural Orissa. Indian J Med Scis 2008;62:364-373.

25. Balgir RS. Intervention and prevention of hereditary hemolytic disorders in India: A case study of two major ethnic communities of Sundargarh district in Orissa. JAPI 2008;56:851-858.

26. Balgir RS. Infant mortality and reproductive wastage associated with different genotypes of hemoglobinopathies in Orissa, India. Ann Hum Biol 2007;34:16-25.

27. Nanda BK, Panda GK, Naik UP, Nanda CN, Praharaj KC. Hemoglobin S in Agharia community of Orissa. J Indian Med Assocn 1967;48:150-152.

28. Das SR, Mukherjee CP, Sastry DB. Sickle cell trait in Koraput district and other parts of India. Acta Genet Stat Med 1967;17:62-73.

29. Roy DN, Roy Chaudhuri SK. Sickle cell trait in the tribal population in Madhya Pradesh and Orissa. J Indian Med Assocn 1967;49:107-112.

Metadata

Repository Staff Only: item control page