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Ocular Surface Squamous Neoplasia in Xeroderma Pigmentosum

Nayak, RR and Kamath, GM and Kamath, MM and Kamath, AR and D'Souza, S (2013) Ocular Surface Squamous Neoplasia in Xeroderma Pigmentosum. [Journal (On-line/Unpaginated)]

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Abstract

Xeroderma pigmentosum (XP) is a rare genetic disorder associated with multiple oculocutaneous and neurological manifestations. It occurs due to deficiency of the enzymes responsible for repairing ultraviolet radiation-induced DNA damage. Persistence of un-repaired DNA results in somatic mutations, leading to neoplasia of the skin and ocular surface. As this condition is rare, only isolated case reports of XP with ocular surface squamous neoplasia (OSSN) are found in literature.

Item Type:Journal (On-line/Unpaginated)
Keywords:Ocular surface squamous neoplasia; Xeroderma pigmentosum
Subjects:JOURNALS > Online Journal of Health and Allied Sciences
ID Code:9702
Deposited By: Kakkilaya Bevinje, Dr. Srinivas
Deposited On:21 Feb 2015 14:35
Last Modified:20 Apr 2015 11:44

References in Article

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1. Trosko JE, Krause D, Isoun M. Sunlight-induced pyrimidine dimmers in human cells in vitro. Nature. 1970;228:358–359.

2. Kraemer KH, Lee MM, Scotto J. Xeroderma pigmentosum — cutaneous, ocular and neurologic abnormalities in 830 published cases. Arch Dermatol. 1987;123:241–250.

3. Lee GA, Hirst LW. Ocular surface squamous neoplasia. Surv Ophthalmol. 1995;39:429–450.

4. Goyal JL, Rao VA, Srinivasan R, Agrawal K. Oculocutaneous manifestations in xeroderma pigmentosa. Br J Ophthalmol. 1994;78:295–297.

5. Basti S, Macsai MS. Ocular surface squamous neoplasia: a review. Cornea. 2003;22:687–704.

6. Eric JC, Campbell RJ, Leisgang J. Conjunctival and corneal intraepithelial and invasive neoplasia. Ophthalmology. 1986;93:176–183.

7. Divine RD, Anderson RL. Nitrous oxide cryotherapy for intraepithelial epithelioma of the conjunctiva. Arch Ophthalmol. 1983;101:782–786.

8. Fraunfelder FT, Wingfield D. Management of intraepithelial epitheliomas and squamous cell carcinomas. Am J Ophthalmol. 1983;95:359–363.

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