Aims This programme will address the public health need a) to provide evidence for more rationally targeting antibiotics to those most likely to benefit and b) to develop better antibiotic and non-antibiotic strategies. Aims This programme will address the public health need a) to provide evidence for more rationally targeting antibiotics to those most likely to benefit and b) to develop better antibiotic and non-antibiotic strategies. Acute infections are the commonest conditions managed in primary care, and most people still receive an antibiotic despite limited evidence for their effectiveness. The overuse of antibiotics creates a major threat to the public health - antibiotic resistance. To move patient care forward we need to a) understand which patients are likely to suffer adversely when antibiotics are not given b) assess the impact of infections and their treatment on quality of life c) assess the effectiveness of alternative antibiotic prescribing strategies and non antibiotic approaches, and d) develop easily accessible information for patients. ECS Research plans: 5) Trial of tailored self management website. We will develop and then perform a moderate sized trial of a robust, theoretically based, interactive and tailored website to alter antibiotic expectations and use. We will develop a website and perform a trial among a minimum of 2000 patients. (A definitive trial will require several thousand patients). A website has the potential for results to be available rapidly nationally and currently 60% of families have access rising by 5% each year.