ECS Intranet:
An electronic-based ELISA combined with microfluidics

Our aim is to develop a low-cost real-time protein detection device to continuously monitor cytokines during in-vitro culture that could eventually expand in clinical practice. We will do this by exploiting discrete electronic components as chemical sensors that are compatible with unique microfluidic chips for minimising the overall cost of the device in combination with small size enzyme-linked immunosorbent assay (ELISA) chambers that minimise antibody requirements. We aspire achieving this by adapting well established manufacturing techniques, currently employed in fabricating printed-circuit boards (PCBs), that could effortlessly render bespoke functionalised electrodes coupled with μm-scale fluidic channels/chambers.

Type: Normal Research Project
Research Groups: Nano Research Group, Southampton Nanofabrication Centre
Themes: Bionanotechnology and Biosensors, Medical Engineering
Dates: 5th May 2014 to 4th May 2017

Keywords

• biosensors
• low-cost manufacturing
• point-of-care diagnostics

Partners

• Peter Kelleher, Department of Medicine, Imperial College London
• Panagiotis Pantelidis, Infection and Immunity, Imperial College Healthcare NHS Trust
• Louise Greathead, Infection and Immunity, Imperial College Healthcare NHS Trust

Funding

• EPSRC

Principal Investigators

• Themistoklis Prodromakis

Other Investigators

• Professor Hywel Morgan

You can edit the record for this project by visiting http://secure.ecs.soton.ac.uk/db/projects/editproj.php?project=892