We investigate the sensitivity of Asymmetry Observables constructed from top pair decay products, specifically in the semileptonic channel, to an underlying Z′ boson arising from U(1) gauge extensions to the Standard Model. We include full tree-level Standard Model background effects and interference. We also account for appropriate experimental cuts and realistic reconstruction efficiencies for the partonic final state decay products, including quark-assignment, and reconstruction of the neutrino momentum. We demonstrate that combinations of spin and charge asymmetries can enable one to distinguish between a selection of benchmark Z′ models, owing to their unique dependencies on chiral couplings to the new gauge boson.