Origin of light neutrino masses and mixing remains a mystery. Within the Standard Model (SM) they remain massless. Simplest extension of SM to this end requires incorporation of heavy right-handed singlets which generate light neutrino masses via Type-1 seesaw mechanism. Interestingly, the heavy neutrinos that decay in a lepton-asymmetric way (leptogenesis) in the early universe, can be fully responsible for the observed baryon asymmetry of the universe. In this talk, I will discuss leptogenesis in Type-1 seesaw within the context of a class of SO(10) grand unification models where the neutrino Dirac masses (coupling between RH singlets, Higgs and lepton doublets) are proportional to up type quark masses. I will explain if the current neutrino oscillation data continues to be so, SO(10)-inspired leptogenesis can be fully tested by cosmological and neutrino less double beta decay experiments during the next years.