Relating the chemical and physical properties of nanoparticles to their cellular toxicity

Date:

2009-

Themes:

Healthcare in ECS, Bionanotechnology and Biosensors

Funding:

Adventure in Research Grant

This ongoing project aims to develop a series of complimentary methods to systematically study the interaction of nanoparticles with synthetic cell membranes, in order to gain an understanding of the role of the physical and chemical properties of nanoparticles, with and without a protein corona, in cellular interactions and to develop an assay that screens for a hallmark of cellular toxicity.

Primary investigators

• Maurits De Planque
• Ms Hend Alkhammash

Secondary investigators

• Dr Jens Madsen (Medicine)
• Dr Philip Williamson (Biological Sciences)

Associated research groups

• Nano Research Group
• Southampton Nanofabrication Centre